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Protein Overview: Jon25Biii-PA

General Information:
Name(s) found: Jon25Biii-PA / FBpp0078692 [FlyBase]
Description(s) found:
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  • gi|7296906|gb|AAF52179.1| jonah 25Biii [Drosophila melanogaster] [NCBI NR]
  • gi|24581774|ref|NP_608881.1| jonah 25Biii [Drosophila melanogaster] [NCBI NR]
  • gi|21064735|gb|AAM29597.1| RH42519p [Drosophila melanogaster] [NCBI NR]
  • gi|18447445|gb|AAL68286.1| RE34302p [Drosophila melanogaster] [NCBI NR]
  • The gene Jonah 25Biii is referred to in FlyBase by the symbol Dmel\Jon25Biii (CG8871, FBgn0031653). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4949947..4950763. It has the cytological map location 25B4. It is reported to have molecular function</span>: endopeptidase activity. It is reported to be involved in the biological process</span>: proteolysis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8871-PA translation from_gene[CG8871 CG8871 FBgn0031653] seq_release:3 mol_weight=27995 cds_boundaries:(2L:4,942,546..4,943,319[-]) aa_length:258 transcript_info:[CG8871-RA seq_release:3] gene_info:[gene symbol:CG8871 FBgn0031653 gene_boundaries:(2L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VMX9) CG8871 protein (RE34302p) (RH42519p) [DrosMelano7227.FASTAC.txt]
  • (AE003608) CG8871 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8871-PA [Drosophila melanogaster]gi|21064735|gb|AAM29597.1| RH42519p [Drosophila melanogaster]gi|18447445|gb|AAL68286.1| RE34302p [Drosophila melanogaster]gi|24581774|ref|NP_608881.1| CG8871-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179; MD5=13a60916574e3 [fly-100309-contam.fasta]
  • RH42519p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8871-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Jonah 25Biii CG8871-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE34302p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Jonah 25Biii OS=Drosophila melanogaster GN=Jon25Biii PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179,FlyMine:FBpp0078692,modMine:FBpp0078692; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179,FlyMine:FBpp0078692,modMine:FBpp0078692; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179,FlyMine:FBpp0078692,modMine:FBpp0078692; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Jonah 25Biii OS=Drosophila melanogaster GN=Jon25Biii PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0078692 type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179,FlyMine:FBpp0078692,modMine:FBpp0078692; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(4949972..4950748); ID=FBpp0078692; name=Jon25Biii-PA; parent=FBgn0031653,FBtr0079056; dbxref=FlyBase:FBpp0078692,FlyBase_Annotation_IDs:CG8871-PA,GB_protein:AAF52179.1,REFSEQ:NP_608881,GB_protein:AAF52179,UniProt/TrEMBL:Q9VMX9,FlyMine:FBpp0078692,modMine:FBpp0078692; MD5=13a60916574e3bfeca78b4c0f6e7294b; length=258; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 258 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    Molecular Function: endopeptidase activity [NAS]
    serine-type endopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVFLAILAL AVASASAFDE KVFVKDLPKA TKIEGRITNG YAAPEGKAPY TVGLGFSGGW  60
   61 WCGGSIIAHD WVLTAEHCIG DAASVIVYFG ATWRTNAQFT HTVGNGNFIK HSNADIALIR 120
  121 IPHVDFWHMV NKVELPSYND RYNNYNEWWA VACGWGGTYD GSPLPDWLQC VDLQIVHNEE 180
  181 CGWTYGSVGD NVICTRTVDG KSICGGDSGG PLVTHDGSKL VGVSNFVSSN GCQSGAPAGF 240
  241 QRVTYHLDWI RDHTGISY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..258] PSI-BLAST 47.69897 HL collagenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • fucose binding
    		•  1.28001086938735 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03130756227487 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • DNA binding
    		•  0.559109234340392 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  0.37880912538686 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  0.126941350425071 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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