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View Structure Prediction Details

Protein: Jon25Biii-PA
Organism: Drosophila melanogaster
Length: 258 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Jon25Biii-PA.

Description E-value Query
Range
Subject
Range
gi|109483412 - gi|109483412|ref|XP_345933.3| PREDICTED: similar to transmembrane protease, serine 4 [Rattus norvegi...
226.0 [0..14] [257..670]
gi|109132475 - gi|109132475|ref|XP_001084459.1| PREDICTED: similar to coagulation factor IX isoform 1 [Macaca mulat...
225.0 [0..35] [257..187]
TMPS6_MOUSE - Transmembrane protease, serine 6 - Mus musculus (Mouse)
223.0 [0..26] [253..554]
gi|58737077 - gi|58737077|dbj|BAD89383.1| coagulation factor IX [Homo sapiens]
223.0 [0..35] [257..187]
gi|220948282 - gi|220948282|gb|ACL86684.1| Jon44E-PA [synthetic construct]
FBpp0311716, Jon... - The gene Jonah 44E is referred to in FlyBase by the symbol Dmel\Jon44E (CG8579, FBgn0001285). It is ...
223.0 [0..1] [258..1]

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Predicted Domain #1
Region A:
Residues: [1-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVFLAILAL AVASASAFDE KVFVKDLPKA TKIEGRITNG YAAPEGKAPY TVGLGFSGGW  60
   61 WCGGSIIAHD WVLTAEHCIG DAASVIVYFG ATWRTNAQFT HTVGNGNFIK HSNADIALIR 120
  121 IPHVDFWHMV NKVELPSYND RYNNYNEWWA VACGWGGTYD GSPLPDWLQC VDLQIVHNEE 180
  181 CGWTYGSVGD NVICTRTVDG KSICGGDSGG PLVTHDGSKL VGVSNFVSSN GCQSGAPAGF 240
  241 QRVTYHLDWI RDHTGISY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1hylA
Description: HL collagenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.91209560688646 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.52773635813967 bayes_pls_golite062009
serine hydrolase activity 5.5105092190926 bayes_pls_golite062009
serine-type peptidase activity 5.49703869306079 bayes_pls_golite062009
serine-type endopeptidase activity 5.39623690248556 bayes_pls_golite062009
endopeptidase activity 5.32070018460528 bayes_pls_golite062009
hydrolase activity 4.40346950809697 bayes_pls_golite062009
glycosaminoglycan binding 2.01328116441763 bayes_pls_golite062009
heparin binding 1.48285358055737 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009
polysaccharide binding 1.34665327732001 bayes_pls_golite062009
binding 1.30738106455622 bayes_pls_golite062009
protein binding 1.30414885212044 bayes_pls_golite062009
fucose binding 1.28001086938735 bayes_pls_golite062009
nucleic acid binding 1.03130756227487 bayes_pls_golite062009
growth factor activity 0.848900101748605 bayes_pls_golite062009
receptor binding 0.79054390509229 bayes_pls_golite062009
DNA binding 0.559109234340392 bayes_pls_golite062009
calcium-dependent protein binding 0.37880912538686 bayes_pls_golite062009
thrombospondin receptor activity 0.126941350425071 bayes_pls_golite062009

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