Protein Overview: Hrs-PC, Hrs-PB

General Information:
Name(s) found:	Hrs-PC / FBpp0088692 [FlyBase] Hrs-PB / FBpp0088691 [FlyBase]
Description(s) found: Found 39 descriptions. SHOW ALL	The gene Hepatocyte growth factor regulated tyrosine kinase substrate is referred to in FlyBase by the symbol Dmel\Hrs (CG2903, FBgn0031450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2739986..2743377. It has the cytological map location 23A3. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: endocytosis; border follicle cell migration. 13 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; wing margin bristle; oocyte; eye photoreceptor cell; wing; endosome; vesicle; larval garland cell. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Hepatocyte growth factor regulated tyrosine kinase substrate is referred to in FlyBase by the symbol Dmel\Hrs (CG2903, FBgn0031450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2739986..2743377. It has the cytological map location 23A3. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: endocytosis; border follicle cell migration. 13 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; wing margin bristle; oocyte; eye photoreceptor cell; wing; endosome; vesicle; larval garland cell. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	760 amino acids
Gene Ontology:
Cellular Component:	early endosome [NAS] endosome [TAS] cytoplasm [NAS] synaptic vesicle [NAS] late endosome [NAS]
Biological Process:	torso signaling pathway [NAS] synaptic vesicle priming [NAS] vesicle organization [NAS] endosome transport [TAS] endosome to lysosome transport [TAS] border follicle cell migration [IMP] synaptic vesicle exocytosis [ISS] negative regulation of epidermal growth factor receptor signaling pathway [NAS] endocytosis [IMP][NAS] intracellular protein transport [IEA] exocytosis [TAS] neurotransmitter secretion [NAS]
Molecular Function:	zinc ion binding [IEA] protein binding [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRSSFDKNL ENATSHLRLE PDWPSILLIC DEINQKDVTP KNAFAAIKKK MNSPNPHSSC  60
   61 YSLLVLESIV KNCGAPVHEE VFTKENCEMF SSFLESTPHE NVRQKMLELV QTWAYAFRSS 120
  121 DKYQAIKDTM TILKAKGHTF PELREADAMF TADTAPNWAD GRVCHRCRVE FTFTNRKHHC 180
  181 RNCGQVFCGQ CTAKQCPLPK YGIEKEVRVC DGCFAALQRP TSGSGGAKSG PRPADSELPA 240
  241 EYLNSTLAQQ VQTPARKTEQ ELKEEEELQL ALALSQSEAE QQKPKLQSLP PAAYRMQQRS 300
  301 PSPEAPPEPK EYHQQPEEAT NPELAKYLNR SYWEQRKISE SSSMASPSAP SPMPPTPQPQ 360
  361 QIMPLQVKSA DEVQIDEFAA NMRTQVEIFV NRMKSNSSRG RSISNDSSVQ TLFMTLTSLH 420
  421 SQQLSYIKEM DDKRMWYEQL QDKLTQIKDS RAALDQLRQE HVEKLRRIAE EQERQRQMQM 480
  481 AQKLDIMRKK KQEYLQYQRQ LALQRIQEQE REMQLRQEQQ KAQYLMGQSA PPFPYMPPSA 540
  541 VPQHGSPSHQ LNNVYNPYAA GVPGYLPQGP APAPNGHGQF QAIPPGMYNP AIQQPMPPNL 600
  601 QPGGLMQQPA PPGNPQMMPP MPENQFANNP AAILQLPQQH SIAQPPQIPF QPQPQQIPGQ 660
  661 QPQQIPGQQP QQIPGQQPQQ IPGQQPQQIP VQQPQPQPQM GHVMLQQHQA PPAAQAPPVT 720
  721 EIANNQVQAV AAAPAPPQNE PGPAPVKAEE PATAELISFD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Hrs-PC, Hrs-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: