Protein Overview: TFE2_RAT

General Information:
Name(s) found:	TFE2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|67508845\|emb\|CAJ00426.1\| pancreas specific transcription factor, 1c [Rattus norvegicus] [NCBI NR] gi\|35279\|emb\|CAA38421.1\| Pan-2 [Rattus norvegicus] [NCBI NR] ref\|NP_598208.1\| transcription factor E2a [Rattus norvegicus] [NCBI NR] gi\|129599\|sp\|P21677.1\|TFE2_RAT RecName: Full=Transcription factor E2-alpha; AltName: Full=Immunoglobulin enhancer-binding factor E12/E47; AltName: Full=Transcription factor 3; Short=TCF-3; AltName: Full=Transcription regulator Pan; AltName: Full=Pancreas [NCBI NR] pir\|\|A35816 transcription regulator Pan-2 - rat [NCBI NR] Transcription factor E2-alpha OS=Rattus norvegicus GN=Tcf3 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7-4023883 Splice isoform E12 of P21677 [hmr_yeast5_DM3-1_pombe.fasta] transcription factor E2a [HMR_022704-rand.fasta] transcription factor E2a [Rattus norvegicus]gi\|35279\|emb\|CAA38421.1\| Pan-2 [Rattus norvegicus]gi\|112424\|pir\|\|A35816 transcription regulator Pan-2 - ratgi\|129599\|sp\|P21677\|TFE2_RAT Transcription factor E2-alpha (Immunoglobulin enhancer binding factor E1 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform E12 of Transcription factor E2-alpha [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_133524) transcription factor E2a [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription regulator Pan) (Pancreas specific transcription factor 1c) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pancreas specific transcription factor, 1c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Pan-2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF TRANSCRIPTION FACTOR E2-ALPHA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription regulator Pan) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Tcfe2a Isoform E12 of Transcription factor E2-alpha [rat-ipi-250309-contam.fasta] Isoform E12 of Transcription factor E2-alpha OS=Rattus norvegicus GN=Tcf3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	649 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA][ISS] transcription factor complex [UNKNOWN][IEA][ISS] cytoplasm [UNKNOWN][ISS] nuclear nucleosome [UNKNOWN][IEA] protein complex [UNKNOWN][ISS] nucleoplasm [UNKNOWN]
Biological Process:	histone H4 acetylation [UNKNOWN][IEA] histone H3 acetylation [UNKNOWN][IEA] immunoglobulin V(D)J recombination [UNKNOWN][IEA] regulation of transcription, DNA-dependent [UNKNOWN] positive regulation of cell cycle [UNKNOWN][ISS] regulation of transcription [UNKNOWN][IEA] B cell lineage commitment [UNKNOWN][IEA][ISS] positive regulation of transcription, DNA-dependent [UNKNOWN][ISS] response to drug [UNKNOWN][IEA] G1 phase of mitotic cell cycle [UNKNOWN][ISS] positive regulation of B cell proliferation [UNKNOWN][ISS] response to lipopolysaccharide [UNKNOWN][IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] protein stabilization [UNKNOWN]
Molecular Function:	identical protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][ISS] sequence-specific DNA binding [UNKNOWN][IEA][ISS] transcription factor binding [UNKNOWN][IPI][ISS] bHLH transcription factor binding [UNKNOWN] DNA binding [UNKNOWN][ISS] transcription factor activity [UNKNOWN][ISS] protein binding [UNKNOWN] transcription regulator activity [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN][IEA] vitamin D response element binding [UNKNOWN] promoter binding [UNKNOWN] E-box binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKGRPAS LAGTQFAGSG LEDRPSSESW  60
   61 GNSEQNSSSF DPSRAYSEGA HFSDSHSSLP PSTFLGAGLG GKGSERNAYA TFGRDTSVGT 120
  121 LSQAGFLPGE LGLSSPGPLS PSGVKSSSQY YTSFPSNPRR RAADGGLDTQ PKKVRKVPPG 180
  181 LPSSVYPSSS GDNYSRDATA YPSAKTPSSA YPSPFYVADG SLHPSAELWS PPGQVGFGPM 240
  241 LGDGSAPLPL APGSSSVSSG AFGGLQQQDR MGYQLHGSEV NGTLPAVSSF SAAPGTYSGT 300
  301 SGHTPPVSGA DSLLGTRGTT ASSSGDALGK ALASIYSPDH SSNNFSPSPS TPVGSPQGLP 360
  361 GTSQWPRAGA PSALSPNYDA GLHGLSKMED RLDEAIHVLR SHAVGTASEL HGLLPGHSTL 420
  421 TTSFAGPMSL GGRHAGLVSG SHPEDGLTSG ASLLHNHASL PSQPSSLPDL SQRPPDSFSG 480
  481 LGRAGVTAGA SEIKREEKED EEVTSVADAE EDKKDLKVPR TRTSPDEDED DLLPPEQKAE 540
  541 REKERRVANN ARERLRVRDI NEAFKELGRM CQLHLSTEKP QTKLLILHQA VAVILSLEQQ 600
  601 VRERNLNPKA ACLKRREEEK VSGVVGDPQL ALSAAHPGLG EAHNPAGHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: TFE2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: