Protein Overview: CP2DI_RAT

General Information:
Name(s) found:	CP2DI_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62471444\|gb\|AAH93609.1\| Cytochrome P450, family 2, subfamily d, polypeptide 4 [Rattus norvegicus] [NCBI NR] gi\|2493368\|sp\|Q64680.1\|CP2DI_RAT RecName: Full=Cytochrome P450 2D18; AltName: Full=CYPIID18; AltName: Full=P450 2D-29/2D-35 [NCBI NR] gi\|19924041\|ref\|NP_612524.1\| cytochrome P450, family 2, subfamily d, polypeptide 4 [Rattus norvegicus] [NCBI NR] gi\|149065778\|gb\|EDM15651.1\| rCG59782, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1200518\|gb\|AAC52883.1\| cytochrome P450 2D18 [NCBI NR] gi\|1200516\|gb\|AAC52882.1\| cytochrome P450 2D18 [NCBI NR] (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450 2D-29/2D-35) [Swiss-Prot] Cytochrome P450 2D18 OS=Rattus norvegicus GN=Cyp2d18 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):7-110666527 Cytochrome P450 2D18 [hmr_yeast5_DM3-1_pombe.fasta] cytochrome P450 2d18; Cytochrome P450, subfamily IID4; Cytochrome P450 subfamily IID4 [HMR_022704-rand.fasta] cytochrome P450 2d18; Cytochrome P450 subfamily IID4; Cytochrome P450, subfamily IID4 [071204_hmrz_cont.fasta] cytochrome P450, family 2, subfamily d, polypeptide 22 [Rattus norvegicus]gi\|1200518\|gb\|AAC52883.1\| cytochrome P450 2D18gi\|1200516\|gb\|AAC52882.1\| cytochrome P450 2D18gi\|2493368\|sp\|Q64680\|CPDI_RAT Cytochrome P450 2D18 (CYPIID18) (P450 2D-29/2D-35) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cytochrome P450 2D18 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_138515) cytochrome P450 2D18 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Cytochrome P450 2D18 (CYPIID18) (P450 2D-29/2D-35) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450, family 2, subfamily d, polypeptide 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cytochrome P450, family 2, subfamily d, polypeptide 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG59782, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450 2D18 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYTOCHROME P450 2D18 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Cytochrome P450, family 2, subfamily d, polypeptide 22 [Rattus norvegicus] [nr-271106-contam.fasta] cytochrome P450, family 2, subfamily d, polypeptide 22 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cyp2d4v1 Cytochrome P450 2D18 [rat-ipi-250309-contam.fasta] Cytochrome P450 2D18 OS=Rattus norvegicus GN=Cyp2d18 [011711_HMR.fasta] Isoform of P13108, Cytochrome P450 2D18 OS=Rattus norvegicus GN=Cyp2d18 PE=2 SV=1 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	500 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] cytoplasm [UNKNOWN][IEA] mitochondrion [UNKNOWN] membrane [IEA] microsome [UNKNOWN][IEA] endoplasmic reticulum [IEA] cellular_component [ND]
Biological Process:	response to organic substance [IEP] dopamine metabolic process [IDA] drug catabolic process [UNKNOWN] negative regulation of metabolic process [UNKNOWN] isoquinoline alkaloid metabolic process [UNKNOWN] alkaloid metabolic process [UNKNOWN] steroid metabolic process [UNKNOWN] alkaloid catabolic process [UNKNOWN] heterocycle metabolic process [UNKNOWN] coumarin metabolic process [UNKNOWN] negative regulation of binding [UNKNOWN] monoterpenoid metabolic process [UNKNOWN] drug metabolic process [UNKNOWN][IDA] oxidation reduction [UNKNOWN][IEA] arachidonic acid metabolic process [IDA] oxidative demethylation [UNKNOWN]
Molecular Function:	arachidonic acid monooxygenase activity [IDA] drug binding [UNKNOWN] oxidoreductase activity [UNKNOWN] metal ion binding [IEA] electron carrier activity [IEA] aromatase activity [IEA] steroid 21-monooxygenase activity [IMP] monooxygenase activity [UNKNOWN][IDA][TAS] heme binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRMPTGSELW PIAIFTIIFL LLVDLMHRRQ RWTSRYPPGP VPWPVLGNLL QIDFQNMPAG  60
   61 FQKLRCRFGD LFSLQLAFES VVVLNGLPAL REALVKYSED TADRPPLHFN DQSGFGPRSQ 120
  121 GVVLARYGPA WRQQRRFSVS TFRHFGLGKK SLEQWVTEEA RCLCAAFADH SGFPFSPNTL 180
  181 LDKAVCNVIA SLLFACRFEY NDPRFIRLLD LLKDTLEEES GFLPMLLNVF PMLLHIPGLL 240
  241 GKVFSGKKAF VAMLDELLTE HKVTWDPAQP PRDLTDAFLA EVEKAKGNPE SSFNDENLRV 300
  301 VVADLFMAGM VTTSTTLTWA LLFMILRPDV QCRVQQEIDE VIGQVRRPEM ADQARMPFTN 360
  361 AVIHEVQRFA DILPLGVPHK TSRDIEVQGF LIPKGTTLII NLSSVLKDET VWEKPLRFHP 420
  421 EHFLDAQGNF VKHEAFMPFS AGRRACLGEP LARMELFLFF TCLLQRFSFS VPAGQPRPSN 480
  481 YGVFGALTTP RPYQLCASPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CP2DI_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: