Protein Overview: KPCZ_RAT

General Information:
Name(s) found:	KPCZ_RAT [Swiss-Prot]
Description(s) found: Found 19 descriptions. SHOW ALL	Protein kinase C zeta type OS=Rattus norvegicus GN=Prkcz PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	592 amino acids
Gene Ontology:
Cellular Component:	tight junction [UNKNOWN][IEA] perinuclear region of cytoplasm [IDA] cytoplasm [UNKNOWN][IEA] cell cortex [UNKNOWN][IEA] membrane raft [IDA] microsome [IDA] cytosol [UNKNOWN][IDA] apical cortex [UNKNOWN][IEA] filamentous actin [IDA] plasma membrane [IDA]
Biological Process:	insulin receptor signaling pathway [IMP] positive regulation of cell proliferation [IMP] protein heterooligomerization [IPI] protein amino acid phosphorylation [UNKNOWN][IDA] cellular response to insulin stimulus [IMP] negative regulation of hydrolase activity [IDA] positive regulation of protein transport [IMP] vesicle transport along microtubule [IMP] negative regulation of protein complex assembly [UNKNOWN][IEA] actin cytoskeleton reorganization [IMP] activation of protein kinase B activity [IMP] negative regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] signal transduction [IDA] positive regulation of synaptic transmission [IMP] positive regulation of glucose import [IMP] cell surface receptor linked signaling pathway [IMP] microtubule cytoskeleton organization [UNKNOWN][IEA] negative regulation of insulin receptor signaling pathway [UNKNOWN][IEA] long-term memory [IMP] intracellular signaling pathway [IDA] positive regulation of cell-matrix adhesion [IMP] negative regulation of apoptosis [IDA] membrane hyperpolarization [IMP] activation of phospholipase D activity [IMP] peptidyl-serine phosphorylation [UNKNOWN][IDA] membrane depolarization [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein kinase binding [IPI] zinc ion binding [IEA] protein binding [UNKNOWN][IDA][IPI] metal ion binding [IEA] phospholipase binding [IPI] protein kinase activity [UNKNOWN][TAS] protein serine/threonine kinase activity [UNKNOWN][IDA] transferase activity [IEA] potassium channel regulator activity [IMP] protein kinase C activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSRTDPKMD RSGGRVRLKA HYGGDILITS VDPTTTFQDL CEEVRDMCGL HQQHPLTLKW  60
   61 VDSEGDPCTV SSQMELEEAF RLACQGRDEV LIIHVFPSIP EQPGMPCPGE DKSIYRRGAR 120
  121 RWRKLYRANG HLFQAKRFNR RAYCGQCSER IWGLARQGYR CINCKLLVHK RCHVLVPLTC 180
  181 RRHMDSVMPS QEPPVDDKND GVDLPSEETD GIAYISSSRK HDNIKDDSED LKPVIDGVDG 240
  241 IKISQGLGLQ DFDLIRVIGR GSYAKVLLVR LKKNDQIYAM KVVKKELVHD DEDIDWVQTE 300
  301 KHVFEQASSN PFLVGLHSCF QTTSRLFLVI EYVNGGDLMF HMQRQRKLPE EHARFYAAEI 360
  361 CIALNFLHER GIIYRDLKLD NVLLDADGHI KLTDYGMCKE GLGPGDTTST FCGTPNYIAP 420
  421 EILRGEEYGF SVDWWALGVL MFEMMAGRSP FDIITDNPDM NTEDYLFQVI LEKPIRIPRF 480
  481 LSVKASHVLK GFLNKDPKER LGCRPQTGFS DIKSHAFFRS IDWDLLEKKQ TLPPFQPQIT 540
  541 DDYGLDNFDT QFTSEPVQLT PDDEDVIKRI DQSEFEGFEY INPLLLSAEE SV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: KPCZ_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: