Protein Overview: GRM4_RAT

General Information:
Name(s) found:	GRM4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JH0563 metabotropic glutamate receptor 4 precursor - rat [NCBI NR] gi\|400255\|sp\|P31423.1\|GRM4_RAT RecName: Full=Metabotropic glutamate receptor 4; Short=mGluR4; Flags: Precursor [NCBI NR] Metabotropic glutamate receptor 4 precursor (mGluR4) - Rattus norvegicus (Rat) [Swiss-Prot] Metabotropic glutamate receptor 4 OS=Rattus norvegicus GN=Grm4 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):20-6511625 Metabotropic glutamate receptor 4 precursor [hmr_yeast5_DM3-1_pombe.fasta] metabotropic glutamate receptor 4 precursor - ratgi\|400255\|sp\|P31423\|MGR4_RAT Metabotropic glutamate receptor 4 precursor (mGluR4) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Metabotropic glutamate receptor 4 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Metabotropic glutamate receptor 4 precursor (mGluR4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 METABOTROPIC GLUTAMATE RECEPTOR 4 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Grm4 Metabotropic glutamate receptor 4 [rat-ipi-250309-contam.fasta] Metabotropic glutamate receptor 4 OS=Rattus norvegicus GN=Grm4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	912 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [UNKNOWN] terminal button [IDA] dendritic shaft [IDA] integral to membrane [IEA] cytoplasmic vesicle [UNKNOWN] presynaptic active zone membrane [IDA] intracellular [UNKNOWN] plasma membrane [IEA]
Biological Process:	negative regulation of adenylate cyclase activity [UNKNOWN] neuroprotection [NAS] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] neuron projection development [TAS] negative regulation of cell proliferation [TAS] negative regulation of synaptic transmission [TAS] inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway [UNKNOWN] gamma-aminobutyric acid secretion [TAS] synaptic transmission [UNKNOWN] positive regulation of MAPKKK cascade [UNKNOWN] learning [UNKNOWN] activation of MAPK activity [UNKNOWN] negative regulation of apoptosis [TAS] synaptic transmission, GABAergic [TAS] synaptic transmission, glutamatergic [TAS]
Molecular Function:	G-protein coupled receptor activity [IEA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGKGGWAWW WARLPLCLLL SLYAPWVPSS LGKPKGHPHM NSIRIDGDIT LGGLFPVHGR  60
   61 GSEGKACGEL KKEKGIHRLE AMLFALDRIN NDPDLLPNIT LGARILDTCS RDTHALEQSL 120
  121 TFVQALIEKD GTEVRCGSGG PPIITKPERV VGVIGASGSS VSIMVANILR LFKIPQISYA 180
  181 STAPDLSDNS RYDFFSRVVP SDTYQAQAMV DIVRALKWNY VSTLASEGSY GESGVEAFIQ 240
  241 KSRENGGVCI AQSVKIPREP KTGEFDKIIK RLLETSNARG IIIFANEDDI RRVLEAARRA 300
  301 NQTGHFFWMG SDSWGSKSAP VLRLEEVAEG AVTILPKRMS VRGFDRYFSS RTLDNNRRNI 360
  361 WFAEFWEDNF HCKLSRHALK KGSHIKKCTN RERIGQDSAY EQEGKVQFVI DAVYAMGHAL 420
  421 HAMHRDLCPG RVGLCPRMDP VDGTQLLKYI RNVNFSGIAG NPVTFNENGD APGRYDIYQY 480
  481 QLRNGSAEYK VIGSWTDHLH LRIERMQWPG SGQQLPRSIC SLPCQPGERK KTVKGMACCW 540
  541 HCEPCTGYQY QVDRYTCKTC PYDMRPTENR TSCQPIPIVK LEWDSPWAVL PLFLAVVGIA 600
  601 ATLFVVVTFV RYNDTPIVKA SGRELSYVLL AGIFLCYATT FLMIAEPDLG TCSLRRIFLG 660
  661 LGMSISYAAL LTKTNRIYRI FEQGKRSVSA PRFISPASQL AITFILISLQ LLGICVWFVV 720
  721 DPSHSVVDFQ DQRTLDPRFA RGVLKCDISD LSLICLLGYS MLLMVTCTVY AIKTRGVPET 780
  781 FNEAKPIGFT MYTTCIVWLA FIPIFFGTSQ SADKLYIQTT TLTVSVSLSA SVSLGMLYMP 840
  841 KVYIILFHPE QNVPKRKRSL KAVVTAATMS NKFTQKGNFR PNGEAKSELC ENLETPALAT 900
  901 KQTYVTYTNH AI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRM4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: