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A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix. A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: presynaptic active zone membrane
Acc: GO:0048787
Aspect: Cellular Component
Desc: The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.
Synonyms:
  • pre-synaptic active zone membrane
  • active zone pre-synaptic plasma membrane
  • active zone plasma membrane
  • active zone presynaptic plasma membrane
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048787 - presynaptic active zone membrane (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle