Protein Overview: TNR1A_RAT

General Information:
Name(s) found:	TNR1A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981664\|ref\|NP_037223.1\| tumor necrosis factor receptor superfamily, member 1a [Rattus norvegicus] [NCBI NR] pir\|\|GQRTT1 tumor necrosis factor receptor 1 precursor - rat [NCBI NR] gi\|207362\|gb\|AAA42256.1\| tumor necrosis factor receptor [NCBI NR] gi\|14091033\|gb\|AAK53562.1\| tumor necrosis factor receptor 1 precursor [Rattus norvegicus] [NCBI NR] gi\|135961\|sp\|P22934.2\|TNR1A_RAT RecName: Full=Tumor necrosis factor receptor superfamily member 1A; AltName: Full=p60; AltName: Full=TNF-R1; AltName: Full=TNF-RI; AltName: Full=TNFR-I; AltName: Full=p55; AltName: CD_antigen=CD120a; Flags: Precursor [NCBI NR] (P22934) Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (p55) [Swiss-Prot] Tumor necrosis factor receptor superfamily member 1A OS=Rattus norvegicus GN=Tnfrsf1a PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):4-167423555 Tumor necrosis factor receptor superfamily member 1A precursor [hmr_yeast5_DM3-1_pombe.fasta] tumor necrosis factor receptor superfamily, member 1a; Tumor necrosis factor receptor [HMR_022704-rand.fasta] tumor necrosis factor receptor superfamily, member 1a [Rattus norvegicus]gi\|14091033\|gb\|AAK53562.1\| tumor necrosis factor receptor 1 precursor [Rattus norvegicus]gi\|135961\|sp\|P22934\|TR1A_RAT Tumor necrosis factor receptor superfamily member 1A precursor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tumor necrosis factor receptor superfamily member 1A precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_013091) Tumor necrosis factor receptor; Tumor necrosis factor receptor superfamily, member 1a [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tumor necrosis factor receptor superfamily, member 1a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tumor necrosis factor receptor 1 precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] tumor necrosis factor receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tnfrsf1a Tumor necrosis factor receptor superfamily member 1A [rat-ipi-250309-contam.fasta] tumor necrosis factor receptor superfamily, member 1a precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Tumor necrosis factor receptor superfamily member 1A OS=Rattus norvegicus GN=Tnfrsf1a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	461 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] membrane raft [UNKNOWN][IDA] integral to membrane [IEA] protein complex [IDA] plasma membrane [UNKNOWN]
Biological Process:	signal transduction [IEA] positive regulation of inflammatory response [UNKNOWN][ISS] response to wounding [IEP] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA] prostaglandin metabolic process [IEA] cell surface receptor linked signaling pathway [UNKNOWN][ISS] protein heterooligomerization [IPI] defense response [UNKNOWN][ISS] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][ISS] defense response to bacterium [UNKNOWN][IEA] positive regulation of angiogenesis [IMP] response to ethanol [IEP] inflammatory response [UNKNOWN][IEP][ISS] cytokine-mediated signaling pathway [UNKNOWN][ISS] apoptosis [IEA] response to lipopolysaccharide [IEP]
Molecular Function:	protein binding [UNKNOWN] tumor necrosis factor receptor activity [UNKNOWN][ISS][NAS] receptor activity [IEA] protein complex binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLPIVPGLL LSLVLLALLM GIHPSGVTGL VPSLGDREKR DNLCPQGKYA HPKNNSICCT  60
   61 KCHKGTYLVS DCPSPGQETV CEVCDKGTFT ASQNHVRQCL SCKTCRKEMF QVEISPCKAD 120
  121 MDTVCGCKKN QFQRYLSETH FQCVDCSPCF NGTVTIPCKE KQNTVCNCHA GFFLSGNECT 180
  181 PCSHCKKNQE CMKLCLPPVA NVTNPQDSGT AVLLPLVIFL GLCLLFFICI SLLCRYPQWR 240
  241 PRVYSIICRD SAPVKEVEGE GIVTKPLTPA SIPAFSPNPG FNPTLGFSTT PRFSHPVSST 300
  301 PISPVFGPSN WHNFVPPVRE VVPTQGADPL LYGSLNPVPI PAPVRKWEDV VAAQPQRLDT 360
  361 ADPAMLYAVV DGVPPTRWKE FMRLLGLSEH EIERLELQNG RCLREAHYSM LEAWRRRTPR 420
  421 HEATLDVVGR VLCDMNLRGC LENIRETLES PAHSSTTHLP R

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TNR1A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: