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Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function. Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages. Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle. null

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tumor necrosis factor receptor activity
Acc: GO:0005031
Aspect: Molecular Function
Desc: Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
Synonyms:
  • TNF receptor activity, type I
  • tumor necrosis factor receptor activity, type II
  • NGF/TNF (6 C-domain) receptor activity
  • TNF receptor activity, type II
  • TNF receptor activity
  • GO:0005033
  • GO:0005032
  • tumor necrosis factor receptor activity, type I
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005031 - tumor necrosis factor receptor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle