General Information: |
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Name(s) found: |
MERL_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 586 amino acids |
Gene Ontology: |
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Cellular Component: |
cleavage furrow
[UNKNOWN]
protein complex [IDA] synapse [IDA] nucleolus [UNKNOWN] cell projection [IEA] plasma membrane [UNKNOWN][IDA] nucleus [UNKNOWN] insoluble fraction [IDA] early endosome [UNKNOWN] adherens junction [UNKNOWN] soluble fraction [IDA] cytoskeleton [IEA] perinuclear region of cytoplasm [UNKNOWN][IDA] cytoplasm [UNKNOWN][IDA][IEA] membrane raft [IDA] ruffle [UNKNOWN] filopodium [UNKNOWN] extrinsic to membrane [IEA] lamellipodium [UNKNOWN] |
Biological Process: |
regulation of hippo signaling pathway
[UNKNOWN]
negative regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN] Schwann cell proliferation [UNKNOWN] negative regulation of MAPKKK cascade [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] negative regulation of cell-cell adhesion [UNKNOWN] odontogenesis of dentine-containing tooth [UNKNOWN] ectoderm development [UNKNOWN] negative regulation of DNA replication [UNKNOWN] negative regulation of protein kinase activity [UNKNOWN] regulation of cell proliferation [UNKNOWN] cell-cell junction organization [UNKNOWN] negative regulation of JAK-STAT cascade [UNKNOWN] negative regulation of tyrosine phosphorylation of Stat5 protein [UNKNOWN] negative regulation of cell growth [IDA][NAS] positive regulation of stress fiber assembly [UNKNOWN] mesoderm formation [UNKNOWN] lens fiber cell differentiation [UNKNOWN] actin cytoskeleton organization [UNKNOWN] |
Molecular Function: |
protein domain specific binding
[IPI]
protein binding [UNKNOWN][IPI] integrin binding [IPI] beta-catenin binding [IPI] binding [IEA] cytoskeletal protein binding [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 IASRMSFSSL KRKQPKTFTV RIVTMDAEME FNCEMKWKGK DLFDLVCRTL GLRETWFFGL 60 61 QYTIKDTVAW LKMDKKVLDH DVSKEEPVTF HFLAKFYPEN AEEELVQEIT QHLFFLQVKK 120 121 QILDEKVYCP PEASVLLASY AVQAKYGDYD PSVHKRGFLA QEELLPKRVI NLYQMTPEMW 180 181 EERITAWYAE HRGRARDEAE MEYLKIAQDL EMYGVNYFTI RNKKGTELLL GVDALGLHIY 240 241 DPENRLTPKI SFPWNEIRNI SYSDKEFTIK PLDKKIDVFK FNSSKLRVNK LILQLCIGNH 300 301 DLFMRRRKAD SLEVQQMKAQ AREEKARKQM ERQRLAREKQ MREEAERSRD EPERRVLHMK 360 361 EEATMANEAL MRSEETADLL AEKAQITEEE AKLLAQKAAE AEQEMQRIKA TAIRTEEEKR 420 421 LMEQKVLEAE VLALKMAEES ERRAKEADQL KQDLQEAREA ERRAKQKLLE IATKPTYPPM 480 481 NPIPAPLPPD IPSFDIIGDS LSFDFKDTDM KRLSMEIEKE KVEYMEKSKH LQEQLNELKT 540 541 EIEALKLKER ETALDILHSE HSDSGTSSKH NTIKKPQAQG RRPICI |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)