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Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell. Any constituent part of a cell, the basic structural and functional unit of all organisms. The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. The cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane. The mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: cleavage furrow
Acc: GO:0032154
Aspect: Cellular Component
Desc: In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.
Proteins in PDR annotated with:
   This term: 54 [Search]
   Term or descendants: 54 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032154 - cleavage furrow (interactive image map)

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