Protein Overview: AA2AR_RAT

General Information:
Name(s) found:	AA2AR_RAT [Swiss-Prot]
Description(s) found: Found 23 descriptions. SHOW ALL	Adenosine receptor A2a OS=Rattus norvegicus GN=Adora2a PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	410 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] postsynaptic density [IDA] Golgi membrane [UNKNOWN] intermediate filament [IDA] neuronal cell body [IDA] plasma membrane [UNKNOWN][IDA] membrane fraction [UNKNOWN][IDA] dendrite [IDA] presynaptic active zone [IDA] postsynaptic membrane [IDA] integral to membrane [IEA] endomembrane system [IDA] asymmetric synapse [IDA] axolemma [IDA] axon [IDA]
Biological Process:	synaptic transmission, cholinergic [IMP] negative regulation of locomotion [IDA] positive regulation of synaptic transmission, GABAergic [UNKNOWN][IEA] negative regulation of cell proliferation [IDA] neuron projection morphogenesis [IDA][IMP] regulation of norepinephrine secretion [IMP] vasodilation [IMP] negative regulation of protein kinase activity [IDA] eating behavior [UNKNOWN][IMP] negative regulation of neuron apoptosis [IDA] negative regulation of alpha-beta T cell activation [UNKNOWN][IEA] astrocyte activation [IMP] induction of apoptosis in response to chemical stimulus [UNKNOWN][IEA] synaptic transmission, dopaminergic [UNKNOWN][IEA] locomotory behavior [UNKNOWN][IMP] regulation of mitochondrial membrane potential [IDA] negative regulation of caspase activity [IDA] regulation of synaptic plasticity [IDA] regulation of calcium ion transport via voltage-gated calcium channel activity [IMP] positive regulation of protein secretion [IDA] positive regulation of synaptic transmission, glutamatergic [IDA] natriuresis [IMP] activation of adenylate cyclase activity [UNKNOWN] diuresis [IMP] positive regulation of circadian sleep/wake cycle, sleep [IDA] positive regulation of acetylcholine secretion [IMP] regulation of excitatory postsynaptic membrane potential [IDA] prepulse inhibition [IMP] G-protein coupled receptor protein signaling pathway [UNKNOWN] signal transduction [IEA] negative regulation of inflammatory response [UNKNOWN][IEA] positive regulation of cAMP biosynthetic process [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IDA] transmembrane receptor protein tyrosine kinase signaling pathway [UNKNOWN] response to alkaloid [IMP] activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IMP] activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IDA] negative regulation of vascular permeability [IMP] adenosine receptor signaling pathway [UNKNOWN][IDA] response to amphetamine [UNKNOWN][IEA] regulation of inhibitory postsynaptic membrane potential [UNKNOWN][IEA] response to caffeine [IDA] membrane depolarization [IMP] positive regulation of glutamate secretion [IDA] synaptic transmission, glutamatergic [IDA]
Molecular Function:	type 5 metabotropic glutamate receptor binding [IPI] G-protein coupled receptor activity [IEA] protein binding [IPI] protein heterodimerization activity [IPI] nonmuscle alpha-actinin binding [IDA] adenosine receptor activity, G-protein coupled [UNKNOWN][IDA][TAS] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSVYITVE LAIAVLAILG NVLVCWAVWI NSNLQNVTNF FVVSLAAADI AVGVLAIPFA  60
   61 ITISTGFCAA CHGCLFFACF VLVLTQSSIF SLLAIAIDRY IAIRIPLRYN GLVTGVRAKG 120
  121 IIAICWVLSF AIGLTPMLGW NNCSQKDGNS TKTCGEGRVT CLFEDVVPMN YMVYYNFFAF 180
  181 VLLPLLLMLA IYLRIFLAAR RQLKQMESQP LPGERTRSTL QKEVHAAKSL AIIVGLFALC 240
  241 WLPLHIINCF TFFCSTCRHA PPWLMYLAII LSHSNSVVNP FIYAYRIREF RQTFRKIIRT 300
  301 HVLRRQEPFQ AGGSSAWALA AHSTEGEQVS LRLNGHPLGV WANGSATHSG RRPNGYTLGL 360
  361 GGGGSAQGSP RDVELPTQER QEGQEHPGLR GHLVQARVGA SSWSSEFAPS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AA2AR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: