Protein Overview: CYTB_RAT

General Information:
Name(s) found:	CYTB_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978715\|ref\|NP_036970.1\| cystatin B [Rattus norvegicus] [NCBI NR] pir\|\|UDRTS cystatin beta - rat [NCBI NR] gi\|55892\|emb\|CAA38534.1\| cystatin beta [Rattus norvegicus] [NCBI NR] gi\|54038778\|gb\|AAH84725.1\| Cystatin B (stefin B) [Rattus norvegicus] [NCBI NR] gi\|220726\|dbj\|BAA01462.1\| cystatin beta [Rattus norvegicus] [NCBI NR] gi\|149043590\|gb\|EDL97041.1\| cystatin B, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|118181\|sp\|P01041.1\|CYTB_RAT RecName: Full=Cystatin-B; AltName: Full=Cystatin-beta; AltName: Full=Stefin-B; AltName: Full=Liver thiol proteinase inhibitor [NCBI NR] Cystatin-B OS=Rattus norvegicus GN=Cstb PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):20-11379065 Cystatin B [hmr_yeast5_DM3-1_pombe.fasta] cystatin B; Cystatin beta [HMR_022704-rand.fasta] cystatin B [Rattus norvegicus]gi\|54038778\|gb\|AAH84725.1\| Cystatin B [Rattus norvegicus]gi\|55892\|emb\|CAA38534.1\| cystatin beta [Rattus norvegicus]gi\|118181\|sp\|P01041\|CYTB_RAT Cystatin B (Liver thiol proteinase inhibitor) (Stefin B) (Cystatin beta)gi\|68 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cystatin B [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012838) cystatin beta [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Cystatin-B (Cystatin-beta) (Stefin-B) (Liver thiol proteinase inhibitor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cystatin B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cystatin beta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cystatin B, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cystatin B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYSTATIN B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Cystatin B (Liver thiol proteinase inhibitor) (Stefin B) (Cystatin beta) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cstb Cystatin-B [rat-ipi-250309-contam.fasta] Cystatin-B OS=Rattus norvegicus GN=Cstb [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	98 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] cytoplasm [UNKNOWN][IEA] nucleolus [UNKNOWN][IEA] intracellular [IEA]
Biological Process:	adult locomotory behavior [UNKNOWN][IEA] regulation of apoptosis [IEP] negative regulation of peptidase activity [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IPI] cysteine-type endopeptidase inhibitor activity [UNKNOWN][TAS] protease binding [UNKNOWN][IEA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MMCGAPSATM PATTETQEIA DKVKSQLEEK ANQKFDVFKA ISFRRQVVAG TNFFIKVDVG 60 61 EEKCVHLRVF EPLPHENKPL TLSSYQTDKE KHDELTYF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..98]	PSI-BLAST	40.522879	Cystatin B (stefin B)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
protease binding	3.05816171871392	bayes_pls_golite062009
binding	1.98021211698364	bayes_pls_golite062009
enzyme inhibitor activity	1.95903133061911	bayes_pls_golite062009
enzyme binding	1.4394131270763	bayes_pls_golite062009
cysteine-type endopeptidase inhibitor activity	1.22451594457354	bayes_pls_golite062009
protein binding	0.823288035712675	bayes_pls_golite062009
structural molecule activity	0.605570282689207	bayes_pls_golite062009
endopeptidase inhibitor activity	0.502159706024347	bayes_pls_golite062009
enzyme regulator activity	0.479748849334581	bayes_pls_golite062009
peptidase inhibitor activity	0.32828147131654	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle