YRC Public Data Repository - Protein Structure Prediction

Protein:	CYTB_RAT
Organism:	Rattus norvegicus
Length:	98 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYTB_RAT.

Description	E-value	Query Range	Subject Range
gi\|74002880 - gi\|74002880\|ref\|XP_545130.2\| PREDICTED: similar to Cystatin A (Stefin A) (Cystatin AS) [Canis famili...	167.0	[0..1]	[98..242]
gi\|30584379, gi\|... - gi\|61370525\|gb\|AAX43510.1\| cystatin B [synthetic construct], gi\|61370519\|gb\|AAX43509.1\| cystatin B [...	167.0	[0..1]	[98..1]
CYTB_PIG - Cystatin-B OS=Sus scrofa GN=CSTB PE=1 SV=1	167.0	[0..1]	[98..1]
CYTB_PONPY - Cystatin-B OS=Pongo pygmaeus GN=CSTB PE=3 SV=1 gi\|23496472 - gi\|23496472\|dbj\|BAC20307.1\| cystatin B [Gorilla gorilla] CSTB - cystatin B (stefin B) CYTB_PANPA - Cystatin-B OS=Pan paniscus GN=CSTB PE=3 SV=1 gi\|123980040, gi... - gi\|61360774\|gb\|AAX41924.1\| cystatin B [synthetic construct], gi\|123994795\|gb\|ABM84999.1\| cystatin B ... CYTB_GORGO - Cystatin-B OS=Gorilla gorilla gorilla GN=CSTB PE=3 SV=1	167.0	[0..1]	[98..1]
gi\|76608397 - gi\|76608397\|ref\|XP_591975.2\| PREDICTED: similar to Cystatin B (Liver thiol proteinase inhibitor) (CP...	166.0	[0..4]	[98..134]
gi\|50729385 - gi\|50729385\|ref\|XP_416492.1\| PREDICTED: similar to cystatin B [Gallus gallus]	166.0	[0..1]	[98..1]
CYTB_PANTR - Cystatin-B OS=Pan troglodytes GN=CSTB PE=3 SV=1	166.0	[0..1]	[98..1]
gi\|23821409 - gi\|23821409\|dbj\|BAC21008.1\| cystatin B [Macaca fuscata] gi\|109065176 - gi\|109065176\|ref\|XP_001104524.1\| PREDICTED: cystatin B (stefin B) [Macaca mulatta] CYTB_MACFU - Cystatin-B OS=Macaca fuscata fuscata GN=CSTB PE=3 SV=1	166.0	[0..1]	[98..1]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMCGAPSATM PATTETQEIA DKVKSQLEEK ANQKFDVFKA ISFRRQVVAG TNFFIKVDVG  60
   61 EEKCVHLRVF EPLPHENKPL TLSSYQTDKE KHDELTYF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.522879
Match:	1stfI
Description:	Cystatin B (stefin B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protease binding	3.05816171871392	bayes_pls_golite062009
binding	1.98021211698364	bayes_pls_golite062009
enzyme inhibitor activity	1.95903133061911	bayes_pls_golite062009
enzyme binding	1.4394131270763	bayes_pls_golite062009
cysteine-type endopeptidase inhibitor activity	1.22451594457354	bayes_pls_golite062009
protein binding	0.823288035712675	bayes_pls_golite062009
structural molecule activity	0.605570282689207	bayes_pls_golite062009
endopeptidase inhibitor activity	0.502159706024347	bayes_pls_golite062009
enzyme regulator activity	0.479748849334581	bayes_pls_golite062009
peptidase inhibitor activity	0.32828147131654	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: