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Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. Any process by which an organism stops, prevents or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity. Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. Any process that stops or reduces the activity of an enzyme.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of peptidase activity
Acc: GO:0010466
Aspect: Biological Process
Desc: Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 93 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010466 - negative regulation of peptidase activity (interactive image map)
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