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Protein Overview: G6PD_RAT

General Information:
Name(s) found: G6PD_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Glucose-6-phosphate 1-dehydrogenase OS=Rattus norvegicus GN=G6pdx PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 515 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    centrosome [UNKNOWN]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN]
    intracellular membrane-bounded organelle [UNKNOWN]
    microsome [IDA]
    cytosol [UNKNOWN][IDA]
    internal side of plasma membrane [UNKNOWN]
    Biological Process: response to food [IEP]
    pentose-phosphate shunt, oxidative branch [UNKNOWN][IMP]
    regulation of multicellular organism growth [UNKNOWN]
    NADPH regeneration [UNKNOWN]
    NADP biosynthetic process [UNKNOWN]
    erythrocyte maturation [UNKNOWN]
    regulation of anti-apoptosis [IDA]
    response to oxidative stress [UNKNOWN]
    response to ethanol [IDA]
    pentose biosynthetic process [UNKNOWN]
    negative regulation of protein amino acid glutathionylation [UNKNOWN]
    pentose-phosphate shunt [UNKNOWN][IDA]
    cholesterol biosynthetic process [UNKNOWN]
    erythrocyte development [UNKNOWN]
    response to organic cyclic substance [IEP]
    vasodilation by angiotensin involved in regulation of systemic arterial blood pressure [UNKNOWN]
    carbohydrate metabolic process [IEA]
    glucose 6-phosphate metabolic process [UNKNOWN][IDA][IMP]
    interleukin-12 production [UNKNOWN]
    angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [UNKNOWN]
    glutathione metabolic process [UNKNOWN]
    cellular response to oxidative stress [UNKNOWN]
    cytokine production [UNKNOWN]
    oxidation reduction [UNKNOWN][IEA]
    ribose phosphate biosynthetic process [UNKNOWN]
    interleukin-10 production [UNKNOWN]
    Molecular Function: glucose binding [UNKNOWN][IDA][IMP]
    NADP or NADPH binding [UNKNOWN][IDA][IMP]
    protein homodimerization activity [UNKNOWN]
    sugar binding [IDA]
    oxidoreductase activity [IEA]
    binding [IEA]
    glucose-6-phosphate dehydrogenase activity [UNKNOWN][IDA][IMP][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEQVALSRT QVCGILREEL YQGDAFHQAD THIFIIMGAS GDLAKKKIYP TIWWLFRDGL  60
   61 LPEDTFIVGY ARSRLTVDDI RKQSEPFFKV TPEERPKLEE FFARNSYVAG QYDDPASYKH 120
  121 LNSHMNALHQ GMQANRLFYL ALPPTVYEAV TKNIQEICMS QTGWNRIIVE KPFGRDLQSS 180
  181 NQLSNHISSL FREDQIYRID HYLGKEMVQN LMVLRFANRI FGPIWNRDNI ACVILTFKEP 240
  241 FGTEGRGGYF DEFGIIRDVM QNHLLQMLCL VAMEKPASTD SDDVRDEKVK VLKCISEVET 300
  301 DNVVLGQYVG NPSGEGEATN GYLDDPTVPH GSTTATFAAA VLYVENERWD GVPFILRCGK 360
  361 ALNERKAEVR LQFRDVAGDI FHQQCKRNEL VIRVQPNEAV YTKMMTKKPG MFFNPEESEL 420
  421 DLTYGNRYKN VKLPDAYERL ILDVFCGSQM HFVRSDELRE AWRIFTPLLH KIDREKPQPI 480
  481 PYVYGSRGPT EADELMKRVG FQYEGTYKWV NPHKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle