General Information: |
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Name(s) found: |
FAK2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 1009 amino acids |
Gene Ontology: |
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Cellular Component: |
growth cone
[IDA]
nucleus [IDA] postsynaptic density [IDA] cytoskeleton [IEA] perinuclear region of cytoplasm [IDA] focal adhesion [IDA] cytoplasm [IEA] cell cortex [IDA] membrane raft [IDA] cell junction [IEA] plasma membrane [IEA] axon [IDA] |
Biological Process: |
activation of Janus kinase activity
[IMP]
signal complex assembly [IEA] peptidyl-tyrosine phosphorylation [IDA] positive regulation of JUN kinase activity [IMP] positive regulation of translation [IMP] epidermal growth factor receptor signaling pathway [IMP] positive regulation of cell proliferation [IEP] actin filament organization [IMP] response to cAMP [IEP] cell adhesion [IMP] protein amino acid phosphorylation [UNKNOWN] stress fiber assembly [IMP] positive regulation of anti-apoptosis [IMP] response to mechanical stimulus [IEP] MAPKKK cascade [IMP] response to ethanol [IEP] response to glucose stimulus [IEP] positive regulation of cell growth [IMP] response to hypoxia [IEP] angiogenesis [IMP] focal adhesion assembly [IMP] activation of Rac GTPase activity [IMP] neuron projection development [IMP] response to osmotic stress [IEP] response to cocaine [IEP] response to hydrogen peroxide [IPI] response to reactive oxygen species [IEP] response to hormone stimulus [IEP] blood vessel endothelial cell migration [IMP] response to stress [IEP] elevation of cytosolic calcium ion concentration [IMP] oxygen and reactive oxygen species metabolic process [IMP] oocyte maturation [IMP] response to drug [IEP] response to calcium ion [IEP] response to lithium ion [IEP] cell differentiation [IEP] glial cell proliferation [IEP] negative regulation of ossification [IMP] response to organic nitrogen [IEP] positive regulation of cell migration [IMP] |
Molecular Function: |
nucleotide binding
[IEA]
ATP binding [IEA] protein binding [UNKNOWN][IEA][IPI] non-membrane spanning protein tyrosine kinase activity [IEA] protein kinase activity [UNKNOWN] transferase activity [IEA] protein complex binding [IPI] signal transducer activity [IEA] 3-phosphoinositide-dependent protein kinase binding [IDA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSGVSEPLSR VKVGTLRPPE GPPEPMVVVP VDVEKEDVRI LKVCFYSNSF NPGKNFKLVK 60 61 CTVQTEIQEI ITSILLSGRI GPNIQLAECY GLRLKHMKSD EIHWLHPQMT VGEVQDKYEC 120 121 LHVEAEWRYD LQIRYLPEDF MESLKEDRTT LLYFYQQLRN DYMQRYASKV SEGMALQLGC 180 181 LELRRFFKDM PHNALDKKSN FELLEKEVGL DLFFPKQMQE NLKPKQFRKM IQQTFQQYAS 240 241 LREEECVMKF FNTLAGFANI DQETYRCELI QGWNITVDLV IGPKGIRQLT SQDTKPTCLA 300 301 EFKQIRSIRC LPLEETQAVL QLGIEGAPQS LSIKTSSLAE AENMADLIDG YCRLQGEHKG 360 361 SLIIHAKKDG EKRNSLPQIP TLNLESRRSH LSESCSIESD IYAEIPDETL RRPGGPQYGV 420 421 AREDVVLNRI LGEGFFGEVY EGVYTNHKGE KINVAVKTCK KDCTLDNKEK FMSEAVIMKN 480 481 LDHPHIVKLI GIIEEEPTWI VMELYPYGEL GHYLERNKNS LKVPTLVLYA LQICKAMAYL 540 541 ESINCVHRDI AVRNILVASP ECVKLGDFGL SRYIEDEDYY KASVTRLPIK WMSPESINFR 600 601 RFTTASDVWM FAVCMWEILS FGKQPFFWLE NKDVIGVLEK GDRLPKPELC PPVLYTLMTR 660 661 CWDYDPSDRP RFTELVCSLS DIYQMERDIA IEQERNARYR PPKILEPTAF QEPPPKPSRP 720 721 KYKHPPQTNL LAPKLQFQVP EGLCASSPTL TSPMEYPSPV NSLHTPPLHR HNVFKRHSMR 780 781 EEDFIRPSSR EEAQQLWEAE KIKMRQVLDR QQKQMVEDSQ WLRREERCLD PMVYMNDKSP 840 841 LTPEKEAGYT EFTGPPQKPP RLGAQSIQPT ANLDRTDDLV YHNVMTLVEA VLELKNKLSQ 900 901 LPPEEYVVVV KNVGLNLRKL IGSVDDLLPS LPASSRTEIE GTQKLLNKDL AELINKMRLA 960 961 QQNAVTSLSE DCKRQMLTAS HTLAVDAKNL LDAVDQAKVV ANLAHPPAE |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.98 |
Source: Reynolds et al. (2008)