Protein Overview: BCAR1_RAT

General Information:
Name(s) found:	BCAR1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8134344\|sp\|Q63767.1\|BCAR1_RAT RecName: Full=Breast cancer anti-estrogen resistance protein 1; AltName: Full=CRK-associated substrate; AltName: Full=p130cas [NCBI NR] gi\|6978709\|ref\|NP_037063.1\| breast cancer anti-estrogen resistance 1 [Rattus norvegicus] [NCBI NR] gi\|559371\|dbj\|BAA06169.1\| Crk-associated substrate, p130 [Rattus norvegicus] [NCBI NR] Breast cancer anti-estrogen resistance protein 1 OS=Rattus norvegicus GN=Bcar1 PE=1 SV=1 [Swiss-Prot] (Q63767) CRK-associated substrate (p130cas) (Breast cancer anti-estrogen resistance 1 protein) [Swiss-Prot] Ensembl_locations(Chr-bp):19-39704122;19-39704122;19-39704122 Splice isoform Long of Q63767 [hmr_yeast5_DM3-1_pombe.fasta] v-crk-associated tyrosine kinase substrate [HMR_022704-rand.fasta] breast cancer anti-estrogen resistance 1 [Rattus norvegicus]gi\|559371\|dbj\|BAA06169.1\| Crk-associated substrate, p130 [Rattus norvegicus]gi\|8134344\|sp\|Q63767\|BCA1_RAT CRK-associated substrate (p130cas) (Breast cancer anti-estrogen resistance 1 protein) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Long of Breast cancer anti-estrogen resistance protein 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform Long of CRK-associated substrate [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_012931) v-crk-associated tyrosine kinase substrate [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] breast cancer anti-estrogen resistance 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Crk-associated substrate, p130 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF CRK-ASSOCIATED SUBSTRATE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Bcar1 Isoform Long of Breast cancer anti-estrogen resistance protein 1 [rat-ipi-250309-contam.fasta] Isoform Long of Breast cancer anti-estrogen resistance protein 1 OS=Rattus norvegicus GN=Bcar1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	968 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][ISS] focal adhesion [UNKNOWN][IDA][IMP] cytoplasm [UNKNOWN][ISS] ruffle [UNKNOWN][ISS] cytosol [UNKNOWN] cell junction [IEA] plasma membrane [IMP] lamellipodium [UNKNOWN][IEA]
Biological Process:	G-protein coupled receptor protein signaling pathway [ISS] insulin receptor signaling pathway [IDA] epidermal growth factor receptor signaling pathway [IDA] actin filament organization [UNKNOWN][ISS] platelet-derived growth factor receptor signaling pathway [ISS] cell adhesion [IEA] nerve growth factor receptor signaling pathway [IDA] antigen receptor-mediated signaling pathway [UNKNOWN][ISS] integrin-mediated signaling pathway [UNKNOWN][ISS] cell migration [UNKNOWN][IMP][ISS] actin cytoskeleton organization [IMP] positive regulation of cell migration [UNKNOWN][ISS] B cell receptor signaling pathway [UNKNOWN][ISS]
Molecular Function:	protein kinase binding [UNKNOWN] protein domain specific binding [IPI] protein binding [UNKNOWN][IPI] protein phosphatase binding [UNKNOWN] SH3 domain binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYLVSVGAG PARRAGGLED VSWGPRVSRR PQSYRAARHV NESLPRSAFR VPAAHGASVT  60
   61 PSAALGSGLP ETQPEAVCRG TEKPRFAEGC KPAASRDKNV LAKALYDNVA ESPDELSFRK 120
  121 GDIMTVLERD TQGLDGWWLC SLHGRQGIVP GNRLKILVGM YDKKPAAPGP GPPATPPQPQ 180
  181 PSLPQGVHTP VPPASQYSPM LPTAYQPQPD NVYLVPTPSK TQQGLYQAPG PNPQFQSPPA 240
  241 KQTSTFSKQT PHHSFPSPAT DLYQVPPGPG SPAQDIYQVP PSAGTGHDIY QVPPSLDTRS 300
  301 WEGTKPPAKV VVPTRVGQGY VYEASQAEQD EYDTPRHLLA PGSQDIYDVP PVRGLLPNQY 360
  361 GQEVYDTPPM AVKGPNGRDP LLDVYDVPPS VEKGLPPSNH HSVYDVPPSV SKDVPDGPLL 420
  421 REETYDVPPA FAKPKPFDPT RHPLILAAPP PDSPPAEDVY DVPPPAPDLY DVPPGLRRPG 480
  481 PGTLYDVPRE RVLPPEVADG SVIDDGVYAV PPPAEREAPT DGKRLSASST GSTRSSQSAS 540
  541 SLEVVVPGRE PLELEVAVET LARLQQGVST TVAHLLDLVG SASGPGGWRS TSEPQEPPVQ 600
  601 DLKAAVAAVH GAVHELLEFA RSAVSSATHT SDRTLHAKLS RQLQKMEDVY QTLVVHGQVL 660
  661 DSGRGGPGFT LDDLDRLVAC SRAVPEDAKQ LASFLHGNAS LLFRRTKAPG PGPEGSSSLH 720
  721 LNPTDKASSI QSRPLPSPPK FTSQDSPDGQ YENSEGGWME DYDYVHLQGK EEFEKTQKEL 780
  781 LEKGNIVRQG KGQLELQQLK QFERLEQEVS RPIDHDLANW TPAQPLVPGR TGGLGPSDRQ 840
  841 LLLFYLEQCE ANLTTLTDAV DAFFTAVATN QPPKIFVAHS KFVILSAHKL VFIGDTLSRQ 900
  901 AKAADVRSKV THYSNLLCDL LRGIVATTKA AALQYPSPSA AQDMVDRVKE LGHSTQQFRR 960
  961 VLGQLAAA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.77

Protein Overview: BCAR1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: