Protein Overview: GABR1_RAT

General Information:
Name(s) found:	GABR1_RAT [Swiss-Prot]
Description(s) found: Found 13 descriptions. SHOW ALL	Gamma-aminobutyric acid type B receptor subunit 1 OS=Rattus norvegicus GN=Gabbr1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	991 amino acids
Gene Ontology:
Cellular Component:	synaptosome [IDA] synaptic vesicle [IDA] microsome [IDA] neuronal cell body [IDA] synapse [IEA] plasma membrane [IEA] endoplasmic reticulum membrane [IDA] soluble fraction [IDA] mitochondrial membrane [IDA] cytoplasm [UNKNOWN][IEA] postsynaptic membrane [IEA] dendritic shaft [IDA] dendritic spine [IDA] membrane raft [IDA] integral to membrane [IEA] cell junction [IEA] axolemma [IDA]
Biological Process:	regulation of glutamate secretion [IDA] negative regulation of adenylate cyclase activity [IMP] positive regulation of growth hormone secretion [IMP] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] negative regulation of cell proliferation [IMP] negative regulation of gamma-aminobutyric acid secretion [IMP] negative regulation of synaptic transmission [IDA] response to nicotine [IEP] response to ethanol [IEP] regulation of cAMP biosynthetic process [IDA] osteoblast differentiation [IMP] negative regulation of epinephrine secretion [IMP] negative regulation of dopamine secretion [IDA]
Molecular Function:	G-protein coupled receptor activity [IEA] GABA-B receptor activity [IDA][IMP] protein binding [UNKNOWN][IPI] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLLLVPLF LRPLGAGGAQ TPNATSEGCQ IIHPPWEGGI RYRGLTRDQV KAINFLPVDY  60
   61 EIEYVCRGER EVVGPKVRKC LANGSWTDMD TPSRCVRICS KSYLTLENGK VFLTGGDLPA 120
  121 LDGARVEFRC DPDFHLVGSS RSVCSQGQWS TPKPHCQVNR TPHSERRAVY IGALFPMSGG 180
  181 WPGGQACQPA VEMALEDVNS RRDILPDYEL KLIHHDSKCD PGQATKYLYE LLYNDPIKII 240
  241 LMPGCSSVST LVAEAARMWN LIVLSYGSSS PALSNRQRFP TFFRTHPSAT LHNPTRVKLF 300
  301 EKWGWKKIAT IQQTTEVFTS TLDDLEERVK EAGIEITFRQ SFFSDPAVPV KNLKRQDARI 360
  361 IVGLFYETEA RKVFCEVYKE RLFGKKYVWF LIGWYADNWF KTYDPSINCT VEEMTEAVEG 420
  421 HITTEIVMLN PANTRSISNM TSQEFVEKLT KRLKRHPEET GGFQEAPLAY DAIWALALAL 480
  481 NKTSGGGGRS GVRLEDFNYN NQTITDQIYR AMNSSSFEGV SGHVVFDASG SRMAWTLIEQ 540
  541 LQGGSYKKIG YYDSTKDDLS WSKTDKWIGG SPPADQTLVI KTFRFLSQKL FISVSVLSSL 600
  601 GIVLAVVCLS FNIYNSHVRY IQNSQPNLNN LTAVGCSLAL AAVFPLGLDG YHIGRSQFPF 660
  661 VCQARLWLLG LGFSLGYGSM FTKIWWVHTV FTKKEEKKEW RKTLEPWKLY ATVGLLVGMD 720
  721 VLTLAIWQIV DPLHRTIETF AKEEPKEDID VSILPQLEHC SSKKMNTWLG ELWSFAVSSD 780
  781 VQRRATVGGD SPICVWPAPE SIFYGYKGLL LLLGIFLAYE TKSVSTEKIN DHRAVGMAIY 840
  841 NVAVLCLITA PVTMILSSQQ DAAFAFASLA IVFSSYITLV VLFVPKMRRL ITRGEWQSET 900
  901 QDTMKTGSST NNNEEEKSRL LEKENRELEK IIAEKEERVS ELRHQLQSRQ QLRSRRHPPT 960
  961 PPDPSGGLPR GPSEPPDRLS CDGSRVHLLY K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GABR1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: