Protein Overview: PRDX2_RAT

General Information:
Name(s) found:	PRDX2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8394432\|ref\|NP_058865.1\| peroxiredoxin 2 [Rattus norvegicus] [NCBI NR] gi\|549132\|sp\|P35704.3\|PRDX2_RAT RecName: Full=Peroxiredoxin-2; AltName: Full=Thioredoxin peroxidase 1; AltName: Full=Thioredoxin-dependent peroxide reductase 1; AltName: Full=Thiol-specific antioxidant protein; Short=TSA [NCBI NR] gi\|514254\|gb\|AAA19959.1\| thiol-specific antioxidant [NCBI NR] pir\|\|A57716 thiol-specific antioxidant - rat [NCBI NR] Peroxiredoxin-2 OS=Rattus norvegicus GN=Prdx2 PE=1 SV=3 [Swiss-Prot] (P35704) Peroxiredoxin 2 (EC 1.11.1.-) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) [Swiss-Prot] Ensembl_locations(Chr-bp):13-10898014 Peroxiredoxin 2 [hmr_yeast5_DM3-1_pombe.fasta] peroxiredoxin 2; thioredoxin peroxidase 1 [HMR_022704-rand.fasta] peroxiredoxin 2 [Rattus norvegicus]gi\|632720\|gb\|AAB32034.1\| TSA=thiol-specific antioxidant [rats, brain, Peptide, 198 aa]gi\|2143993\|pir\|\|A57716 thiol-specific antioxidant - ratgi\|549132\|sp\|P35704\|PDX2_RAT Peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thi [nrdb_11152004_Chlamydomonas] (NM_017169) peroxiredoxin 2; thioredoxin peroxidase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Peroxiredoxin 2 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] peroxiredoxin 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Peroxiredoxin-2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] thiol-specific antioxidant [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PEROXIREDOXIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Prdx2 Peroxiredoxin-2 [rat-ipi-250309-contam.fasta] Peroxiredoxin-2 OS=Rattus norvegicus GN=Prdx2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	198 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] mitochondrion [UNKNOWN] cytosol [IDA]
Biological Process:	negative regulation of oxygen and reactive oxygen species metabolic process [UNKNOWN] negative regulation of NF-kappaB transcription factor activity [UNKNOWN] regulation of apoptosis [UNKNOWN] cell redox homeostasis [IEA] hydrogen peroxide metabolic process [UNKNOWN] hydrogen peroxide catabolic process [UNKNOWN] negative regulation of neuron apoptosis [IMP] thymus development [UNKNOWN] activation of MAPK activity [UNKNOWN] response to oxidative stress [UNKNOWN][IMP] negative regulation of T cell differentiation [UNKNOWN] respiratory burst involved in inflammatory response [UNKNOWN] anti-apoptosis [UNKNOWN] homeostasis of number of cells [UNKNOWN] T cell proliferation [UNKNOWN] response to lipopolysaccharide [UNKNOWN] oxidation reduction [IEA] regulation of hydrogen peroxide metabolic process [UNKNOWN] negative regulation of lipopolysaccharide-mediated signaling pathway [UNKNOWN]
Molecular Function:	peroxidase activity [IEA] protein binding [UNKNOWN] antioxidant activity [UNKNOWN] oxidoreductase activity [IEA] thioredoxin peroxidase activity [UNKNOWN] molecular_function [ND] peroxiredoxin activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGNAHIGK PAPDFTGTAV VDGAFKEIKL SDYRGKYVVL FFYPLDFTFV CPTEIIAFSD  60
   61 HAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTKS LSQNYGVLKN 120
  121 DEGIAYRGLF IIDAKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS 180
  181 DTIKPNVDDS KEYFSKHN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: PRDX2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: