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Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process by which a gene product interacts selectively with DNA (deoxyribonucleic acid).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of NF-kappaB transcription factor activity
Acc: GO:0032088
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
Synonyms:
  • NF-kappaB inhibitor
  • inhibition of NF-kappaB transcription factor
Proteins in PDR annotated with:
   This term: 28 [Search]
   Term or descendants: 28 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032088 - negative regulation of NF-kappaB transcription factor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle