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Protein Overview: SMCA4_RAT

General Information:
Name(s) found: SMCA4_RAT [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Transcription activator BRG1 OS=Rattus norvegicus GN=Smarca4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1613 amino acids

    Gene Ontology:
    Cellular Component: heterochromatin [UNKNOWN]
    nucleus [UNKNOWN][IDA]
    SWI/SNF complex [UNKNOWN][IDA]
    soluble fraction [IDA]
    perichromatin fibrils [UNKNOWN]
    npBAF complex [ISS]
    nuclear euchromatin [UNKNOWN]
    nBAF complex [ISS]
    [NOT]nucleolus [UNKNOWN]
    Biological Process: chromatin modification [IEA]
    nervous system development [IEA]
    vasculogenesis [UNKNOWN]
    glial cell fate determination [UNKNOWN]
    regulation of transcription [IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    positive regulation of transcription factor activity [UNKNOWN]
    nucleosome disassembly [IDA]
    heart trabecula formation [UNKNOWN]
    methylation-dependent chromatin silencing [UNKNOWN]
    negative regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    heart development [UNKNOWN]
    keratinocyte differentiation [UNKNOWN]
    chromatin remodeling [UNKNOWN]
    forebrain development [UNKNOWN]
    blastocyst growth [UNKNOWN]
    hindbrain development [UNKNOWN]
    epidermis morphogenesis [UNKNOWN]
    ATP-dependent chromatin remodeling [IDA]
    blastocyst hatching [UNKNOWN]
    extracellular matrix organization [UNKNOWN]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
    embryonic hindlimb morphogenesis [UNKNOWN]
    Molecular Function: DNA-dependent ATPase activity [UNKNOWN]
    identical protein binding [UNKNOWN]
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IEA]
    helicase activity [IEA]
    chromatin binding [UNKNOWN]
    transcription factor binding [UNKNOWN]
    nucleotide binding [IEA]
    DNA binding [IEA]
    ATP binding [IEA]
    p53 binding [UNKNOWN]
    protein binding [UNKNOWN][IC][IPI]
    protein N-terminus binding [UNKNOWN]
    histone acetyl-lysine binding [UNKNOWN]
    transcription activator activity [UNKNOWN]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPMPTQG  60
   61 PGGYPQDNMH QMHKPMESMH EKGMPDDPRY NQMKGMGMRS GAHTGMGPPP SPMDQHSQGY 120
  121 PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGSDPQ ALGQQNRGPT PFNQNQLHQL 180
  181 RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP 240
  241 GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ 300
  301 KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PLVPLHQKQS RITPIQKPRG 360
  361 LDPVEILQER EYRLQARIVH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV 420
  421 VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL 480
  481 QHAKDFREYH RSVTGKLQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK 540
  541 LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG 600
  601 PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES 660
  661 GSEEEEEEEE EEQPQPAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV 720
  721 SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE 780
  781 MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA 840
  841 RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH 900
  901 YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE 960
  961 TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD1020
 1021 GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG1080
 1081 KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK1140
 1141 TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR1200
 1201 VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDEEE1260
 1261 DEVPDDETVN QMIARHEEEF DLFMRMDLDR RREEARNPKR KPRLMEEDEL PSWIIKDDAE1320
 1321 VERLTCEEEE EKMFGRGSRH RKEVDYSDSL TEKQWLKAIE EGTLEEIEEE VRQKKSSRKR1380
 1381 KRDSEAGSST PTTSTRSRDK DEESKKQKKR GRPPAEKLSP NPPNLTKKMK KIVDAVIKYK1440
 1441 DSSGRQLSEV FIQLPSRKEL PEYYELIRKP VDFKKIKERI RNHKYRSLND LEKDVMLLCQ1500
 1501 NAQTFNLEGS LIYEDSIVLQ SVFTSVRQKI EKEDDSEGEE SEEEEEGEEE GSESESRSVK1560
 1561 VKIKLGRKEK AQDRLKGGRR RPSRGSRAKP VVSDDDSDEE QEEDRSGSGS EED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle