Protein Overview: ECE1_RAT

General Information:
Name(s) found:	ECE1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|1706564\|sp\|P42893.2\|ECE1_RAT RecName: Full=Endothelin-converting enzyme 1; Short=ECE-1 [NCBI NR] Endothelin-converting enzyme 1 OS=Rattus norvegicus GN=Ece1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform A of P42893 [hmr_yeast5_DM3-1_pombe.fasta] Endothelin-converting enzyme 1 (ECE-1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform A of Endothelin-converting enzyme 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF ENDOTHELIN-CONVERTING ENZYME 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ece1 Isoform A of Endothelin-converting enzyme 1 [rat-ipi-250309-contam.fasta] Isoform A of Endothelin-converting enzyme 1 OS=Rattus norvegicus GN=Ece1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	762 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IDA] early endosome [UNKNOWN] endosome [UNKNOWN][IEA] Weibel-Palade body [UNKNOWN][IEA] perinuclear region of cytoplasm [UNKNOWN][IEA] secretory granule [IDA] external side of plasma membrane [UNKNOWN][IDA] integral to membrane [UNKNOWN][IEA] vesicle [IDA] Golgi apparatus [IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	pharyngeal system development [UNKNOWN][IEA] hormone catabolic process [UNKNOWN] embryonic digit morphogenesis [UNKNOWN][IEA] positive regulation of G-protein coupled receptor protein signaling pathway [IMP] heart development [UNKNOWN][IEA] calcitonin catabolic process [UNKNOWN][IEA] endothelin maturation [UNKNOWN][IEA] response to hypoxia [IDA] positive regulation of receptor recycling [UNKNOWN][IEA] bradykinin catabolic process [UNKNOWN][IEA] ear development [UNKNOWN][IEA] proteolysis [IDA] apoptosis [IMP] substance P catabolic process [UNKNOWN][IEA] protein processing [IDA] peptide hormone processing [UNKNOWN] protein maturation by peptide bond cleavage [UNKNOWN]
Molecular Function:	protein homodimerization activity [UNKNOWN][IEA] metal ion binding [IEA] endopeptidase activity [UNKNOWN] peptidase activity [IEA] metalloendopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSLRPPQGL GLQWSSFFLG KKGPGLTVSL PLLASSLQVN FRSPRSGQRC WAARTSVEKR  60
   61 LVVLVTLLAA GLVACLAALG IQYRTRTPPV CLTEACVSVT SSILNSMDPT VDPCQDFFSY 120
  121 ACGGWIKANP VPDGHSRWGT FSNLWEHNQA IIKHLLENST ASASEAEKKA QVYYRACMNE 180
  181 TRIEELRAKP LMELIEKLGG WNITGPWAKD NFQDTLQVVT AHYRTSPFFS VYVSADSKNS 240
  241 NSNVIQVDQS GLGLPSRDYY LNKTENEKVL TGYLNYMVQL GKLLGGGDED SIRPQMQQIL 300
  301 DFETALANIT IPQEKRRDEE LIYHKVTAAE LQTLAPAINW LPFLNAIFYP VEINESEPIV 360
  361 VYDKEYLRQV STLINSTDKC LLNNYMMWNL VRKTSSFLDQ RFQDADEKFM EVMYGTKKTC 420
  421 LPRWKFCVSD TENNLGFALG PMFVKATFAE DSKNIASEII LEIKKAFEES LSTLKWMDED 480
  481 TRRSAKEKAD AIYNMIGYPN FIMDPKELDK VFNDYTAVPD LYFENAMRFF NFSLRVTADQ 540
  541 LRKAPNRDQW SMTPPMVNAY YSPTKNEIVF PAGILQAPFY TRSSPNALNF GGIGVVVGHE 600
  601 LTHAFDDQGR EYDKDGNLRP WWKNSSVEAF KQQTECMVQQ YNNYSVNGEP VNGRHTLGEN 660
  661 IADNGGLKAA YRAYQNWVKK NGAEQILPTL GLTSNQLFFL GFAQVWCSVR TPESSHEGLI 720
  721 TDPHSPSRFR VIGSLSNSKE FSEHFRCPLG SPMNPRHKCE VW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ECE1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: