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Protein Overview: LIS1_RAT

General Information:
Name(s) found: LIS1_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Platelet-activating factor acetylhydrolase IB subunit alpha OS=Rattus norvegicus GN=Pafah1b1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: microtubule cytoskeleton [UNKNOWN]
    cell leading edge [UNKNOWN][IEA]
    kinetochore [UNKNOWN][IEA]
    neuronal cell body [IDA]
    vesicular fraction [IDA]
    astral microtubule [UNKNOWN][IEA]
    microtubule associated complex [UNKNOWN][IEA]
    microtubule [IEA]
    nuclear envelope [UNKNOWN][IDA]
    growth cone [IDA]
    nucleus [IEA]
    insoluble fraction [IDA]
    centrosome [UNKNOWN][IEA]
    nuclear membrane [IEA]
    soluble fraction [IDA]
    cytoskeleton [IEA]
    perinuclear region of cytoplasm [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    cell cortex [UNKNOWN][IEA]
    membrane [IEA]
    spindle [IEA]
    cytosol [UNKNOWN]
    motile primary cilium [UNKNOWN][IEA]
    [NOT]nonmotile primary cilium [UNKNOWN]
    Biological Process: layer formation in the cerebral cortex [UNKNOWN][IEA]
    multicellular organismal development [IEA]
    nervous system development [IEA]
    adult locomotory behavior [UNKNOWN][IEA]
    brain morphogenesis [UNKNOWN][IEA]
    microtubule-based process [UNKNOWN]
    learning or memory [UNKNOWN][IEA]
    neuron migration [UNKNOWN][IMP]
    neuroblast proliferation [UNKNOWN][IEA]
    vesicle transport along microtubule [UNKNOWN][IEA]
    stem cell division [IMP]
    cell migration [UNKNOWN]
    transmission of nerve impulse [UNKNOWN]
    synaptic transmission [UNKNOWN][IEA]
    mitosis [IEA]
    hippocampus development [UNKNOWN][IEA]
    microtubule cytoskeleton organization [UNKNOWN]
    cerebral cortex development [UNKNOWN][IEA]
    corpus callosum morphogenesis [UNKNOWN][IEA]
    transport [IEA]
    nuclear envelope disassembly [UNKNOWN][IEA]
    cell cycle [IEA]
    regulation of Rho GTPase activity [UNKNOWN][IEA]
    establishment of mitotic spindle orientation [UNKNOWN][IEA]
    acrosome assembly [UNKNOWN][IEA]
    lipid catabolic process [IEA]
    cell differentiation [IEA]
    microtubule organizing center organization [UNKNOWN][IEA]
    actin cytoskeleton organization [UNKNOWN][IEA]
    retrograde axon cargo transport [UNKNOWN][IEA]
    neuromuscular process controlling balance [UNKNOWN][IEA]
    Molecular Function: protein binding [UNKNOWN]
    protein homodimerization activity [UNKNOWN][IEA]
    platelet-activating factor acetyltransferase activity [TAS]
    phosphoprotein binding [UNKNOWN][IEA]
    dynein intermediate chain binding [IDA]
    dynein binding [UNKNOWN]
    microtubule binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDMN EELDKKYAGL LEKKWTSVIR  60
   61 LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP VTRVIFHPVF 120
  121 SVMVSASEDA TIKVWDYETG DFERTLKGHT DSVQDISFDH SGKLLASCSA DMTIKLWDFQ 180
  181 GFECIRTMHG HDHNVSSVAI MPNGDHIVSA SRDKTIKMWE VQTGYCVKTF TGHREWVRMV 240
  241 RPNQDGTLIA SCSNDQTVRV WVVATKECKA ELREHEHVVE CISWAPESSY SSISEATGSE 300
  301 TKKSGKPGPF LLSGSRDKTI KMWDVSTGMC LMTLVGHDNW VRGVLFHSGG KFILSCADDK 360
  361 TLRVWDYKNK RCMKTLNAHE HFVTSLDFHK TAPYVVTGSV DQTVKVWECR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle