Protein Overview: CLUS_RAT

General Information:
Name(s) found:	CLUS_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|57241\|emb\|CAA31618.1\| sulfated glycoprotein 2 [Rattus norvegicus] [NCBI NR] gi\|461756\|sp\|P05371.2\|CLUS_RAT RecName: Full=Clusterin; AltName: Full=Sulfated glycoprotein 2; Short=SGP-2; AltName: Full=Dimeric acid glycoprotein; Short=DAG; AltName: Full=Testosterone repressed prostate message 2; Short=TRPM-2; Contains: RecName: Full= [NCBI NR] gi\|207526\|gb\|AAA42299.1\| TRPM-2 [NCBI NR] gi\|207524\|gb\|AAA42298.1\| TRPM-2 [NCBI NR] Clusterin OS=Rattus norvegicus GN=Clu PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):15-44770780 Clusterin precursor [hmr_yeast5_DM3-1_pombe.fasta] sulfated glycoprotein 2 [Rattus norvegicus]gi\|207526\|gb\|AAA42299.1\| TRPM-2gi\|207524\|gb\|AAA42298.1\| TRPM-2gi\|461756\|sp\|P05371\|CLUS_RAT Clusterin precursor (Sulfated glycoprotein 2) (SGP-2) (Dimeric acid glycoprotein) (DAG) (Testosterone repressed prosta [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Clusterin precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053021) clusterin; Testostrone-repressed prostate message 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] (NM_012679) testostrone-repressed prostate message 2; Clusterin [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Clusterin precursor (Sulfated glycoprotein 2) (SGP-2) (Dimeric acid glycoprotein) (DAG) (Testosterone repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain; Clusterin alpha chain] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sulfated glycoprotein 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] TRPM-2 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CLUSTERIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Clu Clusterin [rat-ipi-250309-contam.fasta] Clusterin OS=Rattus norvegicus GN=Clu [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	447 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IEA] perinuclear region of cytoplasm [IDA] mitochondrion [UNKNOWN][IEA] spherical high-density lipoprotein particle [UNKNOWN][IEA] extracellular region [IEA] aggresome [IDA]
Biological Process:	multicellular organismal development [IEA] spermatogenesis [IEA] positive regulation of cell proliferation [IMP] response to wounding [IEP] neuron projection morphogenesis [IMP] positive regulation of cell differentiation [IMP] response to virus [UNKNOWN][IEA] response to stress [IEP] response to oxidative stress [IEP] cell death [IEA] anti-apoptosis [IMP] negative regulation of apoptosis [UNKNOWN] apoptosis [TAS] negative regulation of protein homooligomerization [UNKNOWN][IEA] endocrine pancreas development [IMP] response to misfolded protein [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IDA] misfolded protein binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILLLCVAL LLTWDNGMVL GEQEFSDNEL QELSTQGSRY VNKEIQNAVQ GVKHIKTLIE  60
   61 KTNAERKSLL NSLEEAKKKK EGALDDTRDS EMKLKAFPEV CNETMMALWE ECKPCLKHTC 120
  121 MKFYARVCRS GSGLVGRQLE EFLNQSSPFY FWMNGDRIDS LLESDRQQSQ VLDAMQDSFT 180
  181 RASGIIDTLF QDRFFTHEPQ DIHHFSPMGF PHKRPHFLYP KSRLVRSLMP LSHYGPLSFH 240
  241 NMFQPFFDMI HQAQQAMDVQ LHSPALQFPD VDFLKEGEDD PTVCKEIRHN STGCLKMKGQ 300
  301 CEKCQEILSV DCSTNNPAQA NLRQELNDSL QVAERLTQQY NELLHSLQSK MLNTSSLLEQ 360
  361 LNDQFTWVSQ LANLTQGDDQ YLRVSTVTTH SSDSEVPSRV TEVVVKLFDS DPITVVLPEE 420
  421 VSKDNPKFMD TVAEKALQEY RRKSRME

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CLUS_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: