Protein Overview: FGF2_RAT

General Information:
Name(s) found:	FGF2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506599\|ref\|NP_062178.1\| fibroblast growth factor 2 [Rattus norvegicus] [NCBI NR] pir\|\|A31674 basic fibroblast growth factor precursor - rat [NCBI NR] gi\|204286\|gb\|AAA41210.1\| basic fibroblast growth factor precursor [NCBI NR] gi\|149048761\|gb\|EDM01302.1\| fibroblast growth factor 2, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149048760\|gb\|EDM01301.1\| fibroblast growth factor 2, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|122745\|sp\|P13109.1\|FGF2_RAT RecName: Full=Heparin-binding growth factor 2; Short=HBGF-2; AltName: Full=Basic fibroblast growth factor; Short=BFGF; Flags: Precursor [NCBI NR] Fibroblast growth factor 2 OS=Rattus norvegicus GN=Fgf2 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-114179523 Heparin-binding growth factor 2 precursor [hmr_yeast5_DM3-1_pombe.fasta] fibroblast growth factor 2; basic fibroblast growth factor [HMR_022704-rand.fasta] fibroblast growth factor 2 [Rattus norvegicus]gi\|56204\|emb\|CAA30265.1\| unnamed protein product [Rattus rattus]gi\|92001\|pir\|\|A31674 basic fibroblast growth factor precursor - ratgi\|122745\|sp\|P13109\|FGF2_RAT Heparin-binding growth factor 2 precursor (HBG [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Heparin-binding growth factor 2 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019305) Fibroblast growth factor 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Heparin-binding growth factor 2 precursor (HBGF-2) (Basic fibroblast growth factor) (BFGF) (Prostatropin) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] fibroblast growth factor 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] fibroblast growth factor 2, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] basic fibroblast growth factor precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Fgf2 Heparin-binding growth factor 2 [rat-ipi-250309-contam.fasta] Heparin-binding growth factor 2 OS=Rattus norvegicus GN=Fgf2 [011711_HMR.fasta] Heparin-binding growth factor 2 OS=Rattus norvegicus GN=Fgf2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	154 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] extracellular space [UNKNOWN][IEA] cytoplasm [IDA] extracellular region [UNKNOWN]
Biological Process:	embryonic development [IMP] positive regulation of cardiac muscle cell proliferation [UNKNOWN][IEA] negative regulation of cell proliferation [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IDA] fibroblast growth factor receptor signaling pathway [UNKNOWN][IPI] positive regulation of transcription [IDA] negative regulation of cell death [UNKNOWN][ISS] cell migration involved in sprouting angiogenesis [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] C21-steroid hormone biosynthetic process [IDA] positive regulation of angiogenesis [UNKNOWN][IEA] mammary gland epithelial cell differentiation [UNKNOWN][IEA] activation of MAPKK activity [UNKNOWN][IEA] wound healing [IEP] negative regulation of transcription, DNA-dependent [IDA] positive regulation of cell division [IEA] angiogenesis [UNKNOWN] negative regulation of cell growth [IDA] apoptosis [UNKNOWN][IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] positive regulation of epithelial cell proliferation [UNKNOWN][IEA] lung development [UNKNOWN][IEA] negative regulation of blood vessel endothelial cell migration [UNKNOWN][IEA] signal transduction [IDA] chondroblast differentiation [UNKNOWN] positive regulation of granule cell precursor proliferation [UNKNOWN][IEA] positive regulation of cell fate specification [UNKNOWN] regulation of transcription, DNA-dependent [IDA] synaptic transmission [IDA] intracellular protein kinase cascade [IDA] positive regulation of cell differentiation [UNKNOWN][IEA] positive regulation of blood vessel endothelial cell migration [UNKNOWN][IEA] regulation of retinal cell programmed cell death [UNKNOWN][IEA] nuclear translocation of MAPK [IDA] branching involved in ureteric bud morphogenesis [UNKNOWN][ISS] positive regulation of gene expression [UNKNOWN] positive regulation of protein amino acid phosphorylation [UNKNOWN][IEA] positive regulation of ERK1 and ERK2 cascade [UNKNOWN] induction of an organ [UNKNOWN][IEA] regulation of calcium ion-dependent exocytosis [IDA] glial cell differentiation [UNKNOWN][IEA]
Molecular Function:	growth factor activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] nerve growth factor receptor binding [TAS] heparin binding [IEA] voltage-gated calcium channel activity [IDA] fibroblast growth factor receptor binding [UNKNOWN][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGSITSLP ALPEDGGGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK  60
   61 LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS 120
  121 SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: FGF2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: