Protein Overview: ARBK1_RAT

General Information:
Name(s) found:	ARBK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978465\|ref\|NP_036908.1\| beta-adrenergic receptor kinase 1 [Rattus norvegicus] [NCBI NR] pir\|\|I56531 beta-adrenergic-receptor kinase (EC 2.7.1.126) 1 - rat [NCBI NR] gi\|203098\|gb\|AAA40802.1\| beta-adrenergic receptor kinase 1 [NCBI NR] gi\|114153\|sp\|P26817.1\|ARBK1_RAT RecName: Full=Beta-adrenergic receptor kinase 1; Short=Beta-ARK-1; AltName: Full=G-protein-coupled receptor kinase 2 [NCBI NR] (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.1.126) (Beta-ARK-1) (G-protein coupled receptor kinase 2) [Swiss-Prot] Beta-adrenergic receptor kinase 1 OS=Rattus norvegicus GN=Adrbk1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-206386750 Beta-adrenergic receptor kinase 1 [hmr_yeast5_DM3-1_pombe.fasta] adrenergic receptor kinase, beta 1; G-protein-coupled receptor kinase 2; G-protein-linked receptor kinase (beta adrenergic receptor kinase 1); beta-adrenergic receptor kinase 1 beta ARK1 [HMR_022704-rand.fasta] adrenergic receptor kinase, beta 1 [Rattus norvegicus]gi\|114153\|sp\|P26817\|ARK1_RAT Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (G-protein coupled receptor kinase 2)gi\|2143613\|pir\|\|I56531 beta-adrenergic-receptor kinase (EC 2.7.1.126) 1 - ratgi\|20309 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Beta-adrenergic receptor kinase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012776) adrenergic receptor kinase, beta 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (G-protein-coupled receptor kinase 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adrenergic receptor kinase, beta 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] beta-adrenergic receptor kinase 1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 BETA-ADRENERGIC RECEPTOR KINASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] beta-adrenergic receptor kinase 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Adrbk1 Beta-adrenergic receptor kinase 1 [rat-ipi-250309-contam.fasta] Beta-adrenergic receptor kinase 1 OS=Rattus norvegicus GN=Adrbk1 [011711_HMR.fasta] Beta-adrenergic receptor kinase 1 OS=Rattus norvegicus GN=Adrbk1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	689 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IDA] caveola [IDA] cytoplasm [UNKNOWN][IEA] dendritic shaft [IDA] membrane [UNKNOWN][IEA] dendritic spine [IDA] cytosol [UNKNOWN] synapse [IDA] plasma membrane [UNKNOWN] axon [IDA]
Biological Process:	G-protein coupled receptor protein signaling pathway [UNKNOWN][IDA] signal transduction [IEA] response to organic cyclic substance [IDA] response to hydrogen peroxide [IEP] protein amino acid phosphorylation [UNKNOWN][IDA] aging [IEP] negative regulation of striated muscle contraction [UNKNOWN][IEA] cardiac muscle contraction [UNKNOWN][IEA] tachykinin receptor signaling pathway [UNKNOWN][IEA] negative regulation of G-protein coupled receptor protein signaling pathway [NAS] regulation of the force of heart contraction [UNKNOWN][IEA] response to oxidative stress [IDA] heart development [UNKNOWN][IEA] positive regulation of catecholamine secretion [IDA] desensitization of G-protein coupled receptor protein signaling pathway [UNKNOWN][IDA][TAS] negative regulation of the force of heart contraction by chemical signal [UNKNOWN][IEA] peptidyl-serine phosphorylation [UNKNOWN][IEA] peptidyl-threonine phosphorylation [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [UNKNOWN][IDA] G-protein coupled receptor kinase activity [UNKNOWN][IEA] beta-adrenergic receptor kinase activity [IEA] protein kinase activity [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][TAS] transferase activity [IEA] signal transducer activity [IEA] Edg-2 lysophosphatidic acid receptor binding [UNKNOWN] beta-2 adrenergic receptor binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLEAVLAD VSYLMAMEKS KATPAARASK KILLPEPSIR SVMQKYLEDR GEVTFEKIFS  60
   61 QKLGYLLFRD FYLNHLEEAK PLVEFYEEIE KYEKLETEEE RVVRSREIFD SYIMKELLAC 120
  121 SHPFSKNATE HVQGHLVKKQ VPPDLFQPYI EEICQNLRGD VFHKFIESDK FTRFCQWKNV 180
  181 ELNIHLTMND FSVHRIIGRG GFGEVYGCRK ADTGKMYAMK CLDKKRIKMK QGETLALNER 240
  241 IMLSLVSTGD CPFIVCMSYA FHTPDKLSFI LDLMNGGDLH YHLSQHGVFS EADMRFYAAE 300
  301 IILGLEHMHN RFVVYRDLKP ANILLDEHGH VRISDLGLAC DFSKKKPHAS VGTHGYMAPE 360
  361 VLQKGVAYDS SADWFSLGCM LFKLLRGHSP FRQHKTKDKH EIDRMTLTMA VELPDSFSPE 420
  421 LRSLLEGLLQ RDVNRRLGCL GRGAQEIKES PFFRSLDWQM VFLQKYPPPL IPPRGEVNAA 480
  481 DAFDIGSFDE EDTKGIKLLD SDQELYRNFP LTISERWQQE VAETVFDTIN AETDRLEARK 540
  541 KAKNKQLGHE EDYALGKDCI MHGYMSKMGN PFLTQWQRRY FYLFPNRLEW RGEDEAPQSL 600
  601 LTMEEIQSVE ETQIKERKCL LLKIRGGKQF VLQCDSDPEL VQWKKELRDA YREAQQLVQR 660
  661 VPKMKNKPRS PVVELSKVPL IQRGSANGL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: ARBK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: