Protein Overview: PIM1_RAT

General Information:
Name(s) found:	PIM1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393959\|ref\|NP_058730.1\| non-specific serine/threonine protein kinase [Rattus norvegicus] [NCBI NR] gi\|56903\|emb\|CAA45214.1\| Pim-1 [Rattus norvegicus] [NCBI NR] gi\|149043515\|gb\|EDL96966.1\| proviral integration site 1, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|125567\|sp\|P26794.1\|PIM1_RAT RecName: Full=Proto-oncogene serine/threonine-protein kinase Pim-1 [NCBI NR] pir\|\|S26298 protein kinase (EC 2.7.1.37) pim-1 - rat [NCBI NR] Serine/threonine-protein kinase pim-1 OS=Rattus norvegicus GN=Pim1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):20-8657214 Proto-oncogene serine/threonine-protein kinase pim-1 [hmr_yeast5_DM3-1_pombe.fasta] proviral integration site 1; Pim-1 oncogene [HMR_022704-rand.fasta] proviral integration site 1 [Rattus norvegicus]gi\|56903\|emb\|CAA45214.1\| Pim-1 [Rattus norvegicus]gi\|125567\|sp\|P26794\|PIM1_RAT Proto-oncogene serine/threonine-protein kinase pim-1gi\|112148\|pir\|\|S26298 protein kinase (EC 2.7.1.37) pim-1 - rat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Proto-oncogene serine/threonine-protein kinase Pim-1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017034) pim-1 oncogene [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Proto-oncogene serine/threonine-protein kinase Pim-1 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] proviral integration site 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] proviral integration site 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Pim-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] non-specific serine/threonine protein kinase [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pim1 Proto-oncogene serine/threonine-protein kinase Pim-1 [rat-ipi-250309-contam.fasta] Proto-oncogene serine/threonine-protein kinase pim-1 OS=Rattus norvegicus GN=Pim1 [011711_HMR.fasta] Proto-oncogene serine/threonine-protein kinase pim-1 OS=Rattus norvegicus GN=Pim1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	313 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoplasm [UNKNOWN][ISS]
Biological Process:	cell proliferation [UNKNOWN][ISS] positive regulation of cyclin-dependent protein kinase activity involved in G1/S [UNKNOWN] negative regulation of apoptosis [UNKNOWN][ISS] protein amino acid autophosphorylation [UNKNOWN] negative regulation of transcription factor activity [UNKNOWN][IEA] protein amino acid phosphorylation [UNKNOWN][ISS] cell cycle [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [UNKNOWN][ISS] protein binding [UNKNOWN] metal ion binding [IEA] manganese ion binding [UNKNOWN][ISS] transcription factor binding [UNKNOWN][IEA] protein serine/threonine kinase activity [UNKNOWN][ISS] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLSKINSLA HLRAAPCNDL HANKLAPGKE KEPLESQYQV GPLLGSGGFG SVYSGIRVAD  60
   61 NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSGF SGVIRLLDWF ERPDSFVLIL 120
  121 ERPEPVQDLF DFITERGALQ EELARSFFWQ VLEAVRHCHN CGVLHRDIKD ENILIDLNRG 180
  181 ELKLIDFGSG ALLKDTVYTD FDGTRVYSPP EWIRYHRYHG RSAAVWSLGI LLYDMVCGDI 240
  241 PFEHDEEIVK GQVYFRQRVS SECQHLIRWC LSLRPSDRPS FEEIQNHPWM QDVLLPQATA 300
  301 EIHLHSLSPS PSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Protein Overview: PIM1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: