Protein Overview: P2RX3_RAT

General Information:
Name(s) found:	P2RX3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|I58099 gene P2X3 protein - rat [NCBI NR] gi\|1583867\|prf\|\|2121438A P2X3 purinoceptor [NCBI NR] gi\|149022434\|gb\|EDL79328.1\| rCG26470, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1352690\|sp\|P49654.1\|P2RX3_RAT RecName: Full=P2X purinoceptor 3; Short=P2X3; AltName: Full=ATP receptor; AltName: Full=Purinergic receptor [NCBI NR] gi\|1030065\|emb\|CAA62594.1\| P2X3 [Rattus norvegicus] [NCBI NR] (P49654) P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor) [Swiss-Prot] P2X purinoceptor 3 OS=Rattus norvegicus GN=P2rx3 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-61792484 P2X purinoceptor 3 [hmr_yeast5_DM3-1_pombe.fasta] P2X3 [Rattus norvegicus]gi\|1352690\|sp\|P49654\|P2X3_RAT P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor)gi\|2143750\|pir\|\|I58099 gene P2X3 protein - ratgi\|1583867\|prf\|\|2121438A P2X3 purinoceptor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 P2X purinoceptor 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG26470, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P2X3 purinoceptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] P2X3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 P2X PURINOCEPTOR 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] P2X purinoceptor 3 (ATP receptor) (P2X3) (Purinergic receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=P2rx3 P2X purinoceptor 3 [rat-ipi-250309-contam.fasta] P2X purinoceptor 3 OS=Rattus norvegicus GN=P2rx3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	397 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] synaptosome [IDA] terminal button [IDA] membrane [IEA] dendritic spine [IDA] membrane raft [IDA] rough endoplasmic reticulum [IDA] Golgi apparatus [IDA] neuronal cell body [IDA] neuron projection [UNKNOWN][IDA] intracellular part [UNKNOWN] axon [UNKNOWN]
Biological Process:	response to organic substance [UNKNOWN] sensory perception of taste [UNKNOWN] neuromuscular synaptic transmission [UNKNOWN] response to temperature stimulus [UNKNOWN] response to ATP [UNKNOWN] response to carbohydrate stimulus [UNKNOWN] protein homooligomerization [IDA] synaptic transmission [UNKNOWN] response to cold [UNKNOWN] ion transport [UNKNOWN][IEA] response to heat [UNKNOWN] response to hypoxia [UNKNOWN] cation transport [UNKNOWN] regulation of synaptic plasticity [UNKNOWN] behavioral response to pain [UNKNOWN] urinary bladder smooth muscle contraction [UNKNOWN] peristalsis [UNKNOWN] response to stimulus [UNKNOWN] regulation of action potential in neuron [IDA]
Molecular Function:	extracellular ATP-gated cation channel activity [UNKNOWN][IDA] ion channel activity [IEA] ATP binding [IDA][IEA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCISDFFTY ETTKSVVVKS WTIGIINRAV QLLIISYFVG WVFLHEKAYQ VRDTAIESSV  60
   61 VTKVKGFGRY ANRVMDVSDY VTPPQGTSVF VIITKMIVTE NQMQGFCPEN EEKYRCVSDS 120
  121 QCGPERFPGG GILTGRCVNY SSVLRTCEIQ GWCPTEVDTV EMPIMMEAEN FTIFIKNSIR 180
  181 FPLFNFEKGN LLPNLTDKDI KRCRFHPEKA PFCPILRVGD VVKFAGQDFA KLARTGGVLG 240
  241 IKIGWVCDLD KAWDQCIPKY SFTRLDGVSE KSSVSPGYNF RFAKYYKMEN GSEYRTLLKA 300
  301 FGIRFDVLVY GNAGKFNIIP TIISSVAAFT SVGVGTVLCD IILLNFLKGA DHYKARKFEE 360
  361 VTETTLKGTA STNPVFASDQ ATVEKQSTDS GAYSIGH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: P2RX3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: