Protein Overview: ILK_RAT

General Information:
Name(s) found:	ILK_RAT [Swiss-Prot]
Description(s) found: Found 21 descriptions. SHOW ALL	Integrin-linked protein kinase OS=Rattus norvegicus GN=Ilk PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	452 amino acids
Gene Ontology:
Cellular Component:	cell-cell junction [IDA] focal adhesion [UNKNOWN][IDA] cytoplasm [IDA] terminal button [IDA] dendritic shaft [IDA] stress fiber [IDA] cytosol [UNKNOWN] costamere [IDA] neuronal cell body [IDA] protein complex [IDA] plasma membrane [IEA] axon [IDA]
Biological Process:	cell cycle arrest [IMP] positive regulation of MAP kinase activity [IMP] positive regulation of cell proliferation [UNKNOWN][IMP] neuron projection morphogenesis [IMP] positive regulation of myoblast differentiation [IMP] protein heterooligomerization [IDA][IPI] protein amino acid phosphorylation [UNKNOWN][IDA] negative regulation of protein kinase activity [IMP] fibril organization [IMP] negative regulation of neuron apoptosis [IMP] integrin-mediated signaling pathway [UNKNOWN][IMP] positive regulation of axonogenesis [IMP] establishment or maintenance of epithelial cell apical/basal polarity [UNKNOWN][IEA] negative regulation of smooth muscle cell proliferation [IMP] substrate adhesion-dependent cell spreading [IMP] negative regulation of smooth muscle cell migration [IMP] myelin assembly [IMP] positive regulation of dendrite morphogenesis [IMP] positive regulation of axon extension [IMP] positive regulation of MAPKKK cascade [IMP] cell aging [IMP] regulation of signal transduction [IEA] regulation of actin cytoskeleton organization [IMP] regulation of cell growth [IMP] positive regulation of cell-matrix adhesion [IMP] branching involved in ureteric bud morphogenesis [UNKNOWN][IEA] negative regulation of apoptosis [IMP] negative regulation of cardiac muscle cell apoptosis [IMP] peptidyl-serine phosphorylation [IMP] positive regulation of protein kinase B signaling cascade [IMP] positive regulation of cell migration [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein domain specific binding [IC] protein binding [UNKNOWN][IPI] protein kinase activity [IDA] integrin binding [IPI] SH3 domain binding [IDA] protein serine/threonine kinase activity [UNKNOWN][IDA][IMP] transferase activity [IEA] signal transducer activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI  60
   61 NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAEDLV 120
  121 ANGALVSICN KYGEMPVDKA KAPLRELLRE RAEKMGQNLN RIPYKDTFWK GTTRTRPRNG 180
  181 TLNKHSGIDF KQLNFLAKLN ENHSGELWKG RWQGNDIVVK VLKVRDWSTR KSRDFNEECP 240
  241 RLRIFSHPNV LPVLGACQAP PAPHPTLITH WMPYGSLYNV LHEGTNFVVD QSQAVKFALD 300
  301 MARGMAFLHT LEPLIPRHAL NSRSVMIDED MTARISMADV KFSFQCPGRM YAPAWVAPEA 360
  361 LQKKPEDTNR RSADMWSFAV LLWELVTREV PFADLSNMEI GMKVALEGLR PTIPPGISPH 420
  421 VCKLMKICMN EDPAKRPKFD MIVPILEKMQ DK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ILK_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: