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Protein Overview: CYTS_RAT

General Information:
Name(s) found: CYTS_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Cystatin-S OS=Rattus norvegicus GN=Cst4 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 141 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    secretory granule [IDA]
    extracellular region [IEA]
    Biological Process: negative regulation of cell proliferation [IDA]
    response to wounding [IEP]
    response to antibiotic [IEP]
    response to axon injury [IEP]
    salivary gland development [IEP]
    response to organic cyclic substance [IEP]
    response to chromate [IEP]
    cell development [IEP]
    response to hormone stimulus [IEP]
    response to protozoan [IEP]
    response to drug [IEP]
    cell killing [IDA]
    response to protein stimulus [IEP]
    negative regulation of peptidase activity [IDA]
    Molecular Function: peptidase inhibitor activity [IEA]
    cysteine-type endopeptidase inhibitor activity [IDA][TAS]
    protease binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYLLHAQLF LLTTFILVLN MRLCPVLGHF LGGIEKSSME EEGASEALNY AVNEYNEKNS  60
   61 DLYLSRVVEV KDVQKQVVAG TKFFFDVILG KTICLKTQGD LTNCPLNEEA DQQEHEFCSF 120
  121 VVHDIPWENY IVLLSSSCHS I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..141] PSI-BLAST 36.69897 Cystatin C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine-type endopeptidase inhibitor activity
    		•  5.18960601077151 bayes_pls_golite062009
  • protease binding
    		•  3.73826839062329 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  3.46240889348325 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  2.16387275532719 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  2.10667869451861 bayes_pls_golite062009
  • enzyme binding
    		•  1.6342022584305 bayes_pls_golite062009
  • binding
    		•  1.55087889773804 bayes_pls_golite062009
  • protein binding
    		•  0.823288035712675 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.479748849334581 bayes_pls_golite062009
  • beta-amyloid binding
    		•  0.0968491675668099 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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