General Information: |
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Name(s) found: |
RAF1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 648 amino acids |
Gene Ontology: |
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Cellular Component: |
insoluble fraction
[IDA]
cytosol [UNKNOWN][TAS] plasma membrane [UNKNOWN] |
Biological Process: |
MAPKKK cascade
[IDA][IMP]
heart development [IEP] nerve growth factor receptor signaling pathway [UNKNOWN] response to hypoxia [IDA] cytoskeleton organization [UNKNOWN] signal transduction [IEA] small GTPase mediated signal transduction [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] apoptosis [UNKNOWN] intracellular protein kinase cascade [TAS] Ras protein signal transduction [UNKNOWN] protein amino acid phosphorylation [IDA][IEA][IMP][TAS] |
Molecular Function: |
nucleotide binding
[IEA]
ATP binding [IDA][IEA] protein binding [UNKNOWN][IPI] metal ion binding [IEA] protein heterodimerization activity [IPI] receptor signaling protein activity [IEA] MAP kinase kinase kinase activity [IDA][IMP][TAS] protein serine/threonine kinase activity [IEA] transferase activity [IEA] kinase activity [UNKNOWN] mitogen-activated protein kinase kinase binding [IMP] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MEHIQGAWKT ISNGFGLKDA VFDGSSCISP TIVQQFGYQR RASDDGKLTD SSKTSNTIRV 60 61 FLPNKQRTVV NVRNGMSLHD CLMKALKVRG LQPECCAVFR LLQEHKGKKA RLDWNTDAAS 120 121 LIGEELQVDF LDHVPLTTHN FARKTFLKLA FCDICQKFLL NGFRCQTCGY KFHEHCSTKV 180 181 PTMCVDWSNI RQLLLFPNST ASDSGVPAPP SFTMRRMRES VSRMPASSQH RYSTPHAFTF 240 241 NTSSPSSEGS LSQRQRSTST PNVHMVSTTL PVDSRMIEDA IRSHSESASP SALSSSPNNL 300 301 SPTGWSQPKT PVPAQRERAP GSGTQEKNKI RPRGQRDSSY YWEIEASEVM LSTRIGSGSF 360 361 GTVYKGKWHG DVAVKILKVV DPTPEQLQAF RNEVAVLRKT RHVNILLFMG YMTKDNLAIV 420 421 TQWCEGSSLY KHLHVQETKF QMFQLIDIAR QTAQGMDYLH AKNIIHRDMK SNNIFLHEGL 480 481 TVKIGDFGLA TVKSRWSGSQ QVEQPTGSVL WMAPEVIRMQ DNNPFSFQSD VYSYGIVLYE 540 541 LMTGELPYSH INNRDQIIFM VGRGYASPDL SRLYKNCPKA MKRLVADCVK KVKEERPLFP 600 601 QILSSIELLQ HSLPKINRSA SEPSLHRAAH TEDINACTLT TSPRLPVF |
SHOWING SINGLE HITS. [ Hide Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)