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Protein Overview: FABPL_RAT

General Information:
Name(s) found: FABPL_RAT [Swiss-Prot]
Description(s) found:
Found 35 descriptions.
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  • Fatty acid-binding protein, liver OS=Rattus norvegicus GN=Fabp1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 127 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IDA]
    cytosol [IDA]
    apical cortex [IDA]
    peroxisomal matrix [IDA]
    Biological Process: positive regulation of hydrolase activity [IDA]
    intestinal absorption [IDA]
    long-chain fatty acid transport [IMP]
    positive regulation of fatty acid beta-oxidation [IDA]
    positive regulation of cell proliferation [IEP]
    mitosis [TAS]
    transport [IEP]
    Molecular Function: fatty acid binding [IDA][IPI]
    drug binding [IPI]
    bile acid binding [IMP]
    lysophospholipid transporter activity [IC]
    chromatin binding [UNKNOWN][IEA]
    phospholipid binding [IMP]
    transporter activity [IEA]
    long-chain fatty acid transporter activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFSGKYQVQ SQENFEPFMK AMGLPEDLIQ KGKDIKGVSE IVHEGKKVKL TITYGSKVIH  60
   61 NEFTLGEECE LETMTGEKVK AVVKMEGDNK MVTTFKGIKS VTEFNGDTIT NTMTLGDIVY 120
  121 KRVSKRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 31.69897 Crystal structure of human fatty acid binding protein 1 (FABP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • long-chain fatty acid transporter activity
    		•  5.31242454679135 bayes_pls_golite062009
  • fatty acid transporter activity
    		•  5.05947161650978 bayes_pls_golite062009
  • lysophospholipid transporter activity
    		•  4.87368345652673 bayes_pls_golite062009
  • lipid transporter activity
    		•  4.30505384117861 bayes_pls_golite062009
  • binding
    		•  2.93830472620404 bayes_pls_golite062009
  • bile acid binding
    		•  1.56765865943557 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.48205265725428 bayes_pls_golite062009
  • protein binding
    		•  1.23450129884619 bayes_pls_golite062009
  • retinol transporter activity
    		•  1.2139173346293 bayes_pls_golite062009
  • prostaglandin-D synthase activity
    		•  1.18764036773412 bayes_pls_golite062009
  • lipid binding
    		•  0.936781587098929 bayes_pls_golite062009
  • fatty acid binding
    		•  0.761923641769607 bayes_pls_golite062009
  • retinoid binding
    		•  0.451050759082675 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.394662096985878 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle