Protein Overview: BMP2_RAT

General Information:
Name(s) found:	BMP2_RAT [Swiss-Prot]
Description(s) found: Found 14 descriptions. SHOW ALL	Bone morphogenetic protein 2 OS=Rattus norvegicus GN=Bmp2 PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	393 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IDA] membrane-bounded vesicle [IDA] cytoplasm [IDA] protein complex [IDA] extracellular region [UNKNOWN][IEA]
Biological Process:	embryonic development [UNKNOWN][IEA] BMP signaling pathway involved in heart induction [UNKNOWN] positive regulation of astrocyte differentiation [UNKNOWN][IEA] regulation of transcription [UNKNOWN] ovulation cycle [IEP] inflammatory response [UNKNOWN][IEA] response to retinoic acid [IEP] ossification [IEA] BMP signaling pathway [UNKNOWN][IDA] mesenchymal cell differentiation [UNKNOWN][ISS] positive regulation of bone mineralization [UNKNOWN][IEA] SMAD protein signal transduction [UNKNOWN][ISS] cardiac epithelial to mesenchymal transition [UNKNOWN][IEA] growth [IEA] organ morphogenesis [UNKNOWN][IEA] positive regulation of ossification [UNKNOWN] negative regulation of gene expression [UNKNOWN] positive regulation of gene expression [UNKNOWN] cellular response to growth factor stimulus [UNKNOWN] epithelial to mesenchymal transition [UNKNOWN] positive regulation of neurogenesis [IDA] positive regulation of pathway-restricted SMAD protein phosphorylation [UNKNOWN][IEA] cartilage development [IEA] positive regulation of cartilage development [UNKNOWN] telencephalon development [UNKNOWN] telencephalon regionalization [UNKNOWN] negative regulation of cell proliferation [UNKNOWN][IEA] negative regulation of cell cycle [UNKNOWN][IEA] positive regulation of neuron differentiation [UNKNOWN] positive regulation of transcription [UNKNOWN][IEA] odontogenesis of dentine-containing tooth [UNKNOWN][IEA] positive regulation of osteoblast differentiation [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] pathway-restricted SMAD protein phosphorylation [UNKNOWN][ISS] response to mechanical stimulus [IEP] positive regulation of odontogenesis [UNKNOWN] osteoblast differentiation [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IDA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] bone mineralization [UNKNOWN] negative regulation of gene-specific transcription [UNKNOWN][IEA] cardiac cell differentiation [UNKNOWN][IEA] positive regulation of cell differentiation [UNKNOWN] regulation of odontogenesis of dentine-containing tooth [UNKNOWN] protein destabilization [UNKNOWN] positive regulation of phosphatase activity [UNKNOWN] branching involved in ureteric bud morphogenesis [UNKNOWN][IEA] positive regulation of protein amino acid phosphorylation [UNKNOWN] positive regulation of apoptosis [UNKNOWN] cell fate commitment [UNKNOWN][IEA] positive regulation of endothelial cell proliferation [UNKNOWN]
Molecular Function:	growth factor activity [IDA] protein domain specific binding [IPI] protein homodimerization activity [IDA] cytokine activity [IEA] receptor binding [IMP] retinol dehydrogenase activity [UNKNOWN][IEA] protein binding [UNKNOWN] SMAD binding [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN] phosphatase activator activity [UNKNOWN] transcription activator activity [UNKNOWN][IEA] specific transcriptional repressor activity [UNKNOWN][IEA] BMP receptor binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAGTRCLLV LLLPQVLLGG AAGLIPELGR KKFAGASRPL SRPSEDVLSE FELRLLSMFG  60
   61 LKQRPTPSKD VVVPPYMLDL YRRHSGQPGA LAPDHRLERA ASRANTVLSF HHEEAIEELS 120
  121 EMSGKTSRRF FFNLSSVPTD EFLTSAELQI FREQMQEALG NSSFQHRINI YEIIKPATAS 180
  181 SKFPVTRLLD TRLVTQNTSQ WESFDVTPAV MRWTAQGHTN HGFVVEVAHL EEKPGVSKRH 240
  241 VRISRSLHQD EHSWSQVRPL LVTFGHDGKG HPLHKREKRQ AKHKQRKRLK SSCKRHPLYV 300
  301 DFSDVGWNDW IVAPPGYHAF YCHGECPFPL ADHLNSTNHA IVQTLVNSVN SKIPKACCVP 360
  361 TELSAISMLY LDENEKVVLK NYQDMVVEGC GCR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: BMP2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: