Protein Overview: ID2_RAT

General Information:
Name(s) found:	ID2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|729808\|sp\|P41137.1\|ID2_RAT RecName: Full=DNA-binding protein inhibitor ID-2; AltName: Full=Inhibitor of DNA binding 2 [NCBI NR] gi\|6981072\|ref\|NP_037192.1\| inhibitor of DNA binding 2 [Rattus norvegicus] [NCBI NR] gi\|55562879\|gb\|AAH86391.1\| Inhibitor of DNA binding 2 [Rattus norvegicus] [NCBI NR] pir\|\|JC2112 helix-loop-helix protein, Id2 - rat [NCBI NR] gi\|434791\|dbj\|BAA01634.1\| ID2 protein [Rattus norvegicus] [NCBI NR] gi\|149051024\|gb\|EDM03197.1\| inhibitor of DNA binding 2 [Rattus norvegicus] [NCBI NR] DNA-binding protein inhibitor ID-2 OS=Rattus norvegicus GN=Id2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):6-35656595 DNA-binding protein inhibitor ID-2 [hmr_yeast5_DM3-1_pombe.fasta] inhibitor of DNA binding 2 [HMR_022704-rand.fasta] Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [Rattus norvegicus]gi\|6981072\|ref\|NP_037192.1\| inhibitor of DNA binding 2 [Rattus norvegicus]gi\|543397\|pir\|\|JC2112 helix-loop-helix protein, Id2 - ratgi\|434791\|dbj\|BAA01634.1\| ID2 p [nrdb_11152004_Chlamydomonas] Tax_Id=10116 DNA-binding protein inhibitor ID-2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_013060) inhibitor of DNA binding 2, dominant negative helix-loop-helix protein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] ID2 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] inhibitor of DNA binding 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Inhibitor of DNA binding 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 DNA-BINDING PROTEIN INHIBITOR ID-2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Id2 DNA-binding protein inhibitor ID-2 [rat-ipi-250309-contam.fasta] DNA-binding protein inhibitor ID-2 OS=Rattus norvegicus GN=Id2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	134 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] cytoplasm [UNKNOWN] cytosol [IDA] chromatin [IDA]
Biological Process:	multicellular organismal development [IEA] positive regulation of cell proliferation [IDA] enucleate erythrocyte differentiation [UNKNOWN] positive regulation of cell cycle [IDA] negative regulation of transcription factor activity [UNKNOWN] bundle of His development [UNKNOWN] regulation of transcription [IEA] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] heart development [UNKNOWN] cellular response to lithium ion [UNKNOWN] positive regulation of macrophage differentiation [UNKNOWN] negative regulation of transcription [UNKNOWN] response to protein stimulus [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IPI] transcription regulator activity [IDA] protein heterodimerization activity [IC] transcription repressor activity [UNKNOWN]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVT 60 61 KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQTSR TPLTTLNTDI SILSLQASEF 120 121 PSELMSNDSK VLCG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..134]	PSI-BLAST	10.0	Max protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transcription regulator activity	5.38658950816179	bayes_pls_golite062009
DNA binding	5.18654839258297	bayes_pls_golite062009
nucleic acid binding	5.05768805749761	bayes_pls_golite062009
transcription factor activity	4.78039531631248	bayes_pls_golite062009
binding	3.81829206350975	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.39500382187264	bayes_pls_golite062009
protein binding	2.64975291677725	bayes_pls_golite062009
transcription factor binding	2.61163564741984	bayes_pls_golite062009
transcription repressor activity	2.58751248599889	bayes_pls_golite062009
transcription activator activity	2.5495467409976	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	2.42306484786159	bayes_pls_golite062009
sequence-specific DNA binding	2.31910036997977	bayes_pls_golite062009
transcription corepressor activity	2.03674713048499	bayes_pls_golite062009
transcription cofactor activity	1.52770895937238	bayes_pls_golite062009
promoter binding	0.8576109846276	bayes_pls_golite062009
protein heterodimerization activity	0.53175615551166	bayes_pls_golite062009
transcription coactivator activity	0.3513586903977	bayes_pls_golite062009
protein dimerization activity	0.20674648626116	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle