Protein Overview: NPM_RAT

General Information:
Name(s) found:	NPM_RAT [Swiss-Prot]
Description(s) found: Found 26 descriptions. SHOW ALL	Nucleophosmin OS=Rattus norvegicus GN=Npm1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	292 amino acids
Gene Ontology:
Cellular Component:	granular component [UNKNOWN] nucleus [UNKNOWN][ISS] spindle pole centrosome [UNKNOWN] centrosome [UNKNOWN][ISS] ribonucleoprotein complex [UNKNOWN] cytoplasm [UNKNOWN][ISS] nuclear speck [UNKNOWN] cytosol [UNKNOWN] small ribosomal subunit [UNKNOWN] large ribosomal subunit [UNKNOWN] nucleolus [UNKNOWN][IDA] nucleoplasm [UNKNOWN][IEA]
Biological Process:	centrosome cycle [UNKNOWN][ISS] negative regulation of cell proliferation [UNKNOWN][ISS] positive regulation of cell proliferation [UNKNOWN] protein localization [UNKNOWN] positive regulation of DNA replication [IDA] positive regulation of NF-kappaB transcription factor activity [UNKNOWN] cell volume homeostasis [UNKNOWN] regulation of anti-apoptosis [IMP] nucleocytoplasmic transport [UNKNOWN] negative regulation of nuclear mRNA splicing, via spliceosome [UNKNOWN] regulation of cell cycle [UNKNOWN] regulation of DNA damage response, signal transduction by p53 class mediator [UNKNOWN] protein homooligomerization [IDA] cell aging [UNKNOWN][ISS] nucleosome assembly [UNKNOWN] response to stress [UNKNOWN] ribosomal small subunit export from nucleus [UNKNOWN] ribosomal large subunit export from nucleus [UNKNOWN] rRNA export from nucleus [UNKNOWN] positive regulation of cellular biosynthetic process [UNKNOWN] regulation of centrosome duplication [UNKNOWN] positive regulation of catalytic activity [IDA] positive regulation of protein kinase activity [UNKNOWN] negative regulation of centrosome duplication [UNKNOWN] ribosomal large subunit biogenesis [UNKNOWN] positive regulation of centrosome duplication [UNKNOWN] ribosomal small subunit biogenesis [UNKNOWN] positive regulation of DNA metabolic process [IDA] cell growth [UNKNOWN] protein oligomerization [UNKNOWN]
Molecular Function:	protein homodimerization activity [UNKNOWN] ribosomal small subunit binding [UNKNOWN] ribosomal large subunit binding [UNKNOWN] unfolded protein binding [UNKNOWN][ISS] nucleic acid binding [IEA] phosphatidylinositol-3,4,5-trisphosphate binding [IPI] NF-kappaB binding [UNKNOWN][ISS] DNA binding [IDA] RNA binding [UNKNOWN][IEA] protein binding [UNKNOWN] transcription coactivator activity [UNKNOWN] Tat protein binding [UNKNOWN] histone binding [UNKNOWN] protein heterodimerization activity [UNKNOWN] rRNA binding [UNKNOWN] enzyme binding [IDA][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV  60
   61 EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE 120
  121 EDAESEDEDE EDVKLLGMSG KRSAPGGGNK VPQKKVKLDE DDDEDDEDDE DDEDDDDDDF 180
  181 DEEETEEKVP VKKSVRDTPA KNAQKSNQNG KDLKPSTPRS KGQESFKKQE KTPKTPKGPS 240
  241 SVEDIKAKMQ ASIEKGGSLP KVEAKFINYV KNCFRMTDQE AIQDLWQWRK SL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NPM_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: