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Protein Overview: S10A1_RAT

General Information:
Name(s) found: S10A1_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Protein S100-A1 OS=Rattus norvegicus GN=S100a1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 94 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    cytoplasm [IEA]
    sarcoplasmic reticulum [UNKNOWN][IEA]
    cytosol [TAS]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMP]
    Molecular Function: S100 alpha binding [UNKNOWN][IEA]
    S100 beta binding [UNKNOWN][IEA]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN][IPI]
    protein homodimerization activity [UNKNOWN][NAS]
    calcium ion binding [TAS]
    ATPase binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSELETAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSSFLDVQK DADAVDKIMK  60
   61 ELDENGDGEV DFQEFVVLVA ALTVACNNFF WENS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] PSI-BLAST 21.69897 Calcyclin (S100)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • S100 alpha binding
    		•  4.10422481094917 bayes_pls_golite062009
  • binding
    		•  3.17556402087346 bayes_pls_golite062009
  • metal ion binding
    		•  2.62077305565026 bayes_pls_golite062009
  • cation binding
    		•  2.62077305565026 bayes_pls_golite062009
  • ion binding
    		•  2.61312132078717 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  2.41193763776922 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.23156041569913 bayes_pls_golite062009
  • protein binding
    		•  2.21291432166051 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.83723964306928 bayes_pls_golite062009
  • DNA binding
    		•  1.73924929536227 bayes_pls_golite062009
  • S100 beta binding
    		•  1.55177531533958 bayes_pls_golite062009
  • peptidase activity
    		•  1.42397628411744 bayes_pls_golite062009
  • calcium ion binding
    		•  1.40919295397643 bayes_pls_golite062009
  • structural molecule activity
    		•  1.26857768455914 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.24311821191924 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.15266823079004 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11607939838219 bayes_pls_golite062009
  • receptor binding
    		•  0.857448001471136 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.833336205861396 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.787740261079819 bayes_pls_golite062009
  • kinase activity
    		•  0.782396352346639 bayes_pls_golite062009
  • transporter activity
    		•  0.751717017963896 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.654002071540024 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.573179802647827 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.373421951050343 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.27738240687034 bayes_pls_golite062009
  • hydrolase activity
    		•  0.275235036575339 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.23313435855689 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.15563262257885 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle