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View Structure Prediction Details

Protein: S10A1_RAT
Organism: Rattus norvegicus
Length: 94 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for S10A1_RAT.

Description E-value Query
Range
Subject
Range
gi|50761685 - gi|50761685|ref|XP_429152.1| PREDICTED: similar to S100Z protein [Gallus gallus]
120.0 [0..1] [93..367]
gi|76612513 - gi|76612513|ref|XP_595126.2| PREDICTED: similar to Calgizzarin (S100 calcium-binding protein A11) (S...
117.0 [0..2] [94..86]
gi|109016674 - gi|109016674|ref|XP_001108718.1| PREDICTED: similar to Protein S100-A11 (S100 calcium-binding protei...
116.0 [0..2] [93..440]
gi|113431910 - gi|113431910|emb|CAJ90906.1| s100 calcium binding protein [Salmo salar]
114.0 [0..1] [91..26]
gi|114559755 - gi|114559755|ref|XP_513820.2| PREDICTED: S100 calcium binding protein A1 isoform 2 [Pan troglodytes]
112.0 [0..1] [94..54]
gi|56205585, gi|... - gi|56205585|emb|CAI19674.1| S100 calcium binding protein A1 [Homo sapiens], gi|119573686|gb|EAW53301...
112.0 [0..1] [94..54]
gi|34811430, gi|... - gi|34811430|pdb|1NSH|B Chain B, Solution Structure Of Rabbit Apo-S100a11 (19 Models), gi|34811429|pd...
112.0 [0..2] [94..3]
gi|94471603 - gi|94471603|gb|ABF21069.1| mitochondrial calcium sensor cameleon 4mtD3cpv [synthetic construct]
111.0 [0..1] [82..434]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSELETAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSSFLDVQK DADAVDKIMK  60
   61 ELDENGDGEV DFQEFVVLVA ALTVACNNFF WENS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1k2hA
Description: Calcyclin (S100)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S100 alpha binding 4.10422481094917 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
metal ion binding 2.62077305565026 bayes_pls_golite062009
cation binding 2.62077305565026 bayes_pls_golite062009
ion binding 2.61312132078717 bayes_pls_golite062009
calcium-dependent protein binding 2.41193763776922 bayes_pls_golite062009
transcription regulator activity 2.23156041569913 bayes_pls_golite062009
protein binding 2.21291432166051 bayes_pls_golite062009
nucleic acid binding 1.83723964306928 bayes_pls_golite062009
DNA binding 1.73924929536227 bayes_pls_golite062009
S100 beta binding 1.55177531533958 bayes_pls_golite062009
peptidase activity 1.42397628411744 bayes_pls_golite062009
calcium ion binding 1.40919295397643 bayes_pls_golite062009
structural molecule activity 1.26857768455914 bayes_pls_golite062009
transcription repressor activity 1.24311821191924 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.15266823079004 bayes_pls_golite062009
signal transducer activity 1.11607939838219 bayes_pls_golite062009
molecular transducer activity 1.11607939838219 bayes_pls_golite062009
receptor binding 0.857448001471136 bayes_pls_golite062009
endopeptidase activity 0.833336205861396 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.787740261079819 bayes_pls_golite062009
kinase activity 0.782396352346639 bayes_pls_golite062009
transporter activity 0.751717017963896 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.654002071540024 bayes_pls_golite062009
transmembrane transporter activity 0.573179802647827 bayes_pls_golite062009
substrate-specific transporter activity 0.373421951050343 bayes_pls_golite062009
cytoskeletal protein binding 0.27738240687034 bayes_pls_golite062009
hydrolase activity 0.275235036575339 bayes_pls_golite062009
structural constituent of muscle 0.23313435855689 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.15563262257885 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle