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Protein Overview: FGF10_RAT

General Information:
Name(s) found: FGF10_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Fibroblast growth factor 10 OS=Rattus norvegicus GN=Fgf10 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 215 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][ISS]
    extracellular space [UNKNOWN][IEA]
    extracellular matrix [UNKNOWN][IEA]
    extracellular region [UNKNOWN][IEA]
    cellular_component [ND]
    plasma membrane [UNKNOWN][IEA]
    cell surface [UNKNOWN]
    Biological Process: protein localization at cell surface [UNKNOWN][IEA]
    branching involved in lung morphogenesis [UNKNOWN][IEA]
    regulation of prostatic bud formation [UNKNOWN][IEA]
    positive chemotaxis [UNKNOWN][IEA]
    epidermis development [UNKNOWN][IEA]
    muscle cell fate commitment [UNKNOWN][IEA]
    fibroblast growth factor receptor signaling pathway [UNKNOWN][TAS]
    positive regulation of Ras protein signal transduction [UNKNOWN][IEA]
    blood vessel morphogenesis [UNKNOWN]
    embryonic digestive tract morphogenesis [UNKNOWN][IEA]
    branching morphogenesis of a tube [UNKNOWN]
    branching involved in salivary gland morphogenesis [UNKNOWN]
    regulation of smoothened signaling pathway [UNKNOWN][IEA]
    urothelial cell proliferation [UNKNOWN]
    activation of MAPK activity [UNKNOWN][IEA]
    regulation of activin receptor signaling pathway [UNKNOWN][IEA]
    lung alveolus development [UNKNOWN][IEA]
    wound healing [UNKNOWN]
    positive regulation of gene-specific transcription [UNKNOWN]
    epithelial cell proliferation [UNKNOWN]
    embryonic gut development [UNKNOWN][IEA]
    lacrimal gland development [UNKNOWN][IEA]
    positive regulation of lymphocyte proliferation [UNKNOWN][IEA]
    mesonephros development [UNKNOWN][IEA]
    positive regulation of vascular endothelial growth factor receptor signaling pathway [UNKNOWN][IEA]
    regulation of epithelial cell proliferation [UNKNOWN][IEA]
    positive regulation of epithelial cell proliferation [UNKNOWN]
    positive regulation of hair follicle cell proliferation [UNKNOWN]
    positive regulation of urothelial cell proliferation [UNKNOWN][ISS]
    positive regulation of DNA repair [UNKNOWN][IEA]
    lung saccule development [UNKNOWN][IEA]
    embryonic camera-type eye development [UNKNOWN][IEA]
    embryonic pattern specification [UNKNOWN][IEA]
    cell-cell signaling [UNKNOWN][IEA]
    response to organic cyclic substance [IEP]
    organ morphogenesis [UNKNOWN]
    bronchiole morphogenesis [UNKNOWN][IEA]
    epithelial cell differentiation [UNKNOWN][IEA]
    tear secretion [UNKNOWN][IEA]
    mesenchymal cell differentiation involved in lung development [UNKNOWN]
    inner ear morphogenesis [UNKNOWN][IEA]
    induction of an organ [UNKNOWN][IEA]
    regulation of gene expression [UNKNOWN][IEA]
    response to estradiol stimulus [IEP]
    limb morphogenesis [UNKNOWN][IEA]
    positive regulation of Wnt receptor signaling pathway [UNKNOWN][IEA]
    organ growth [UNKNOWN][IEA]
    respiratory system development [UNKNOWN]
    negative regulation of cell proliferation [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN]
    secretion by lung epithelial cell involved in lung growth [UNKNOWN]
    spleen development [UNKNOWN][IEA]
    positive regulation of DNA replication [UNKNOWN][IEA]
    salivary gland development [UNKNOWN][IEA]
    epithelial cell proliferation involved in salivary gland morphogenesis [UNKNOWN][IEA]
    positive regulation of Notch signaling pathway [UNKNOWN][IEA]
    regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [UNKNOWN][IEA]
    regulation of saliva secretion [UNKNOWN][IEA]
    salivary gland morphogenesis [UNKNOWN]
    thymus development [UNKNOWN][IEA]
    lung morphogenesis [UNKNOWN]
    branch elongation involved in salivary gland morphogenesis [UNKNOWN][IEA]
    positive regulation of cyclin-dependent protein kinase activity involved in G1/S [UNKNOWN][IEA]
    chemotaxis [UNKNOWN]
    positive regulation of keratinocyte proliferation [UNKNOWN][IEA]
    smooth muscle cell differentiation [UNKNOWN][IEA]
    angiogenesis [IEP]
    negative regulation of cell differentiation [UNKNOWN][IEA]
    negative regulation of cell cycle arrest [UNKNOWN][IEA]
    Harderian gland development [UNKNOWN]
    positive regulation of keratinocyte migration [UNKNOWN][IEA]
    positive regulation of epithelial cell migration [UNKNOWN]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    response to protein stimulus [UNKNOWN]
    epithelial cell migration [UNKNOWN][IEA]
    actin cytoskeleton reorganization [UNKNOWN][IEA]
    positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA]
    lung development [UNKNOWN]
    pancreas development [UNKNOWN][IEA]
    induction of positive chemotaxis [UNKNOWN][IEA]
    keratinocyte proliferation [UNKNOWN]
    positive regulation of ATPase activity [UNKNOWN][IEA]
    limb development [UNKNOWN]
    limb bud formation [UNKNOWN]
    mammary gland bud formation [UNKNOWN][IEA]
    positive regulation of MAPKKK cascade [UNKNOWN]
    tissue regeneration [IEP]
    determination of left/right symmetry [UNKNOWN][IEA]
    ERK1 and ERK2 cascade [UNKNOWN]
    blood vessel remodeling [UNKNOWN][IEA]
    metanephros development [UNKNOWN][IEA]
    positive regulation of ERK1 and ERK2 cascade [UNKNOWN][IEA]
    cell differentiation [IEP]
    response to lipopolysaccharide [IEP]
    Molecular Function: growth factor activity [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    chemoattractant activity [UNKNOWN][IEA]
    heparin binding [UNKNOWN][ISS]
    type 2 fibroblast growth factor receptor binding [UNKNOWN][IEA]
    transcription activator activity [UNKNOWN]
    fibroblast growth factor receptor binding [UNKNOWN][ISS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKWILTHCA SAFPHLPGCC CCFLLLFLVS SVPVTCQALG QDMVSPEATN SSSSSSSSSS  60
   61 SSSFSSPSSA GRHVRSYNHL QGDVRWRKLF SFTKYFLKIE KNGKVSGTKK ENCPYSILEI 120
  121 TSVEIGVVAV KAINSNYYLA MNKKGKLYGS KEFNNDCKLK ERIEENGYNT YASFNWQHNG 180
  181 RQMYVALNGK GAPRRGQKTR RKNTSAHFLP MVVHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle