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Protein Overview: HXA7_RAT

General Information:
Name(s) found: HXA7_RAT [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Homeobox protein Hox-A7 (Fragment) OS=Rattus norvegicus GN=Hoxa7 PE=3 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 105 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    transcription factor complex [UNKNOWN]
    cytoplasm [UNKNOWN]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IEA]
    mammary gland development [UNKNOWN]
    negative regulation of keratinocyte differentiation [IEA]
    multicellular organismal development [IEA]
    anterior/posterior pattern formation [UNKNOWN][IEA]
    regulation of transcription, DNA-dependent [IEA]
    positive regulation of transcription from RNA polymerase II promoter [IEA]
    embryonic skeletal system development [UNKNOWN]
    embryonic forelimb morphogenesis [UNKNOWN]
    proximal/distal pattern formation [UNKNOWN]
    embryonic skeletal system morphogenesis [IEA]
    definitive hemopoiesis [UNKNOWN]
    Molecular Function: transcription factor activity [IEA]
    protein binding [UNKNOWN][IEA]
    sequence-specific DNA binding [IEA]
    transcription repressor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPDGKRGRQ TYTRYQTLEL EKEFHFNRYL TRRRAVEIAH ALCLTERQIK IWFQNRRMKW  60
   61 KKEHKDESQA PTAVPEDAVP SVSTAADKAD EEEEEEEEEE EEEEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 17.522879 DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.82910876106939 bayes_pls_golite062009
  • DNA binding
    		•  2.71139715874068 bayes_pls_golite062009
  • binding
    		•  2.59102816487173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.4041998404334 bayes_pls_golite062009
  • transcription factor activity
    		•  2.30605638403993 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.81835017168096 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.46122830109379 bayes_pls_golite062009
  • protein binding
    		•  0.853351196918381 bayes_pls_golite062009
  • transcription activator activity
    		•  0.81440394306575 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.77814500281111 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.57338514991304 bayes_pls_golite062009
  • transcription factor binding
    		•  0.22865859991459 bayes_pls_golite062009
  • chromatin binding
    		•  0.203837749053719 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle