Protein Overview: ERAP1_RAT

General Information:
Name(s) found:	ERAP1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8131850\|gb\|AAF73106.1\|AF148323_1 aminopeptidase PILS [Rattus norvegicus] [NCBI NR] gi\|20137194\|sp\|Q9JJ22.2\|ERAP1_RAT RecName: Full=Endoplasmic reticulum aminopeptidase 1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=ARTS-1; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucy [NCBI NR] Endoplasmic reticulum aminopeptidase 1 OS=Rattus norvegicus GN=Erap1 PE=2 SV=2 [Swiss-Prot] Adipocyte-derived leucine aminopeptidase precursor - Rattus norvegicus (Rat) [Swiss-Prot] (Q9JJ22) Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A-LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) [Swiss-Prot] Ensembl_locations(Chr-bp):2-28083 Splice isoform 1 of Q9JJ22 [hmr_yeast5_DM3-1_pombe.fasta] aminopeptidase PILS [Rattus norvegicus]gi\|20137194\|sp\|Q9JJ22\|ART1_RAT Adipocyte-derived leucine aminopeptidase precursor (A-LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Adipocyte-derived leucine aminopeptidase precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Endoplasmic reticulum aminopeptidase 1 (Adipocyte-derived leucine aminopeptidase) (A-LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aminopeptidase PILS [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF ADIPOCYTE-DERIVED LEUCINE AMINOPEPTIDASE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Adipocyte-derived leucine aminopeptidase precursor (A-LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Erap1 Isoform 1 of Endoplasmic reticulum aminopeptidase 1 [rat-ipi-250309-contam.fasta] Isoform 1 of Endoplasmic reticulum aminopeptidase 1 OS=Rattus norvegicus GN=Erap1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	930 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] endoplasmic reticulum lumen [IDA] cytoplasm [UNKNOWN][IEA] membrane [IEA] microsome [IDA] integral to membrane [IEA] endoplasmic reticulum [IEA] extracellular region [UNKNOWN][ISS]
Biological Process:	response to bacterium [UNKNOWN] membrane protein ectodomain proteolysis [UNKNOWN][ISS] proteolysis [IMP] antigen processing and presentation [TAS] positive regulation of angiogenesis [UNKNOWN][IEA]
Molecular Function:	zinc ion binding [IMP] protein binding [UNKNOWN] metal ion binding [IEA] metalloexopeptidase activity [UNKNOWN][ISS] aminopeptidase activity [UNKNOWN][IMP][ISS] peptidase activity [IEA] interleukin-6 receptor binding [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLLSLVLT FLAVSSPSCC QNSDTASPKA SNGASFPWNN MRLPEYITPI HYDLMIHANL  60
   61 STLTFWGKTE VEITVSQPTS TIIMHSHQLQ ISKATLRRGA EEMLPEEPLK LMEYSAHEQV 120
  121 ALLTAQPLLA GSVYTVIITY AANLSENFHG FYKSTYRTQE GERRILAATQ FEPTAARMAF 180
  181 PCFDEPALKA SFSIKIKRDP RHLAISNMPL VKSVTVAEGL IEDHFDITVK MSTYLVAFII 240
  241 SDFKSVSKMT KSGVKVSVYA VPDKINQADY ALDAAVTLLE FYEDYFSIPY PLPKQDLAAI 300
  301 PDFQSGAMEN WGLTTYRESA LLYDKEKSSA SSKLGITMTV SHELAHQWFG NLVTMEWWND 360
  361 LWLNEGFAKF MEFVSVTVTH PELKVEEYFF GKCFNAMEVD ALNSSHPVST PVENPAQIRE 420
  421 MFDEVSYEKG ACILNMLRDY LSADTFKRGI VQYLQKYSYK NTKNEDLWNS MMHICPTDGT 480
  481 QTMDGFCSRN QHSSSTSHWR QEVIDIKSMM NTWTLQKGFP LITITVRGRN VHLKQEHYMK 540
  541 GSECFPETGS LWHVPLTFIT SKSDSVQRFL LKTKTDVIIL PEAVEWIKFN VGMNGYYIVH 600
  601 YGDDGWASLN GLLKEAHTTI SSNDRASLIN NAFQLVSIGK LSIEKALDLI LYLKNETEIM 660
  661 PIFQGLNELI PMYKLMEKRD MVEVETQFKD FLLRLLKDLI NKQTWTDEGS VSERMLRSQL 720
  721 LLLACVHRYQ LCVQRAERYF REWKASNGNM SLPIDVTLAV FAVGAQNTEG WDFLYSKYQS 780
  781 SLSSTEKSQI EFSLCISQDP EKLQWLLDQS FKGEIIKTQE FPHILTLIGR NPVGYPLAWK 840
  841 FLKENWNKIV QKFELGSSSI AHMVMGTTNQ FSTRARLEEV KGFFSSLKKN GSQLRCVQQT 900
  901 IETIEENIRW MDKNFDKIRL WLQKERQELL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ERAP1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: