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Protein Overview: B2L10_MOUSE

General Information:
Name(s) found: B2L10_MOUSE [Swiss-Prot]
Description(s) found:
Found 28 descriptions.
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  • Bcl-2-like protein 10 OS=Mus musculus GN=Bcl2l10 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 191 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN]
    nucleus [IEA]
    mitochondrion [IEA]
    membrane [IEA]
    integral to membrane [IEA]
    Biological Process: anti-apoptosis [UNKNOWN][IDA]
    apoptosis [IDA]
    regulation of apoptosis [IEA]
    [NOT]induction of apoptosis via death domain receptors [UNKNOWN]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSQDPLHE RTRRLLSDYI FFCAREPDTP EPPPTSVEAA LLRSVTRQIQ QEHQEFFSSF  60
   61 CESRGNRLEL VKQMADKLLS KDQDFSWSQL VMLLAFAGTL MNQGPYMAVK QKRDLGNRVI 120
  121 VTRDCCLIVN FLYNLLMGRR HRARLEALGG WDGFCRFFKN PLPLGFWRRL LIQAFLSGFF 180
  181 ATAIFFIWKR L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] PSI-BLAST 46.09691 Proapoptotic molecule Bax

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • BH3 domain binding
    		•  2.69016495057203 bayes_pls_golite062009
  • binding
    		•  2.59561200514645 bayes_pls_golite062009
  • BH domain binding
    		•  2.27237827754342 bayes_pls_golite062009
  • caspase inhibitor activity
    		•  2.08013825948248 bayes_pls_golite062009
  • protein binding
    		•  1.99315623629974 bayes_pls_golite062009
  • protein dimerization activity
    		•  1.73789508200675 bayes_pls_golite062009
  • death domain binding
    		•  1.68707791178093 bayes_pls_golite062009
  • caspase regulator activity
    		•  1.49377208228548 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  1.28226471040487 bayes_pls_golite062009
  • cysteine-type endopeptidase inhibitor activity
    		•  1.14864482798901 bayes_pls_golite062009
  • protease binding
    		•  0.775628666218753 bayes_pls_golite062009
  • identical protein binding
    		•  0.464207026816411 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0304736434950499 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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