Protein Overview: DRD1_MOUSE

General Information:
Name(s) found:	DRD1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|33859542\|ref\|NP_034206.1\| dopamine receptor D1A [Mus musculus] [NCBI NR] gi\|31340533\|sp\|Q61616.2\|DRD1_MOUSE RecName: Full=D(1A) dopamine receptor [NCBI NR] gi\|26336735\|dbj\|BAC32050.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|187952675\|gb\|AAI37656.1\| Dopamine receptor D1A [Mus musculus] [NCBI NR] gi\|187950727\|gb\|AAI37642.1\| Dopamine receptor D1A [Mus musculus] [NCBI NR] D(1A) dopamine receptor OS=Mus musculus GN=Drd1 PE=1 SV=2 [Swiss-Prot] (Q61616) D(1A) dopamine receptor [Swiss-Prot] Ensembl_locations(Chr-bp):None D [hmr_yeast5_DM3-1_pombe.fasta] dopamine receptor D1A; D1 receptor [HMR_022704-rand.fasta] D(1A) dopamine receptor [ipi.MOUSE.v3.06.fasta] dopamine receptor D1A [Mus musculus]gi\|26336735\|dbj\|BAC32050.1\| unnamed protein product [Mus musculus]gi\|31340533\|sp\|Q61616\|DADR_MOUSE D(1A) dopamine receptor [nrdb_11152004_Chlamydomonas] Tax_Id=10090 D(1A) dopamine receptor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] dopamine receptor D1A [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Dopamine receptor D1A [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 D(1A) DOPAMINE RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Drd1a D(1A) dopamine receptor [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Drd1a D(1A) dopamine receptor ENSMUSG00000021478 IPI00123490 [IPIxENS.MOUSE_plus_REVERSE.fasta] D(1A) dopamine receptor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00123490.2\|SWISS-PROT:Q61616\|TREMBL:B2RPW8;Q80T33;Q9QZQ9\|ENSEMBL:ENSMUSP00000021932\|REFSEQ:NP_034206 Tax_Id=10090 Gene_Symbol=Drd1a D(1A) dopamine receptor [ipi.MOUSE.fasta.20090209] d(1A) dopamine receptor [Mus musculus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] D(1A) dopamine receptor OS=Mus musculus GN=Drd1 [011711_HMR.fasta] D(1A) dopamine receptor OS=Mus musculus GN=Drd1 PE=2 SV=2 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|Q61616\|DRD1_MOUSE D(1A) dopamine receptor OS=Mus musculus GN=Drd1 PE=2 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	446 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] dendrite [UNKNOWN] nucleus [IDA] caveola [UNKNOWN] membrane [IEA] dendritic spine [UNKNOWN] integral to membrane [UNKNOWN] endoplasmic reticulum [UNKNOWN] neuronal cell body [UNKNOWN] plasma membrane [UNKNOWN] axon [UNKNOWN]
Biological Process:	dopamine transport [IMP] dopamine receptor signaling pathway [UNKNOWN][IGI][IMP] visual learning [UNKNOWN][IMP] striatum development [IMP] intracellular protein transport [UNKNOWN] associative learning [UNKNOWN][IMP] learning [IMP] memory [IMP] regulation of ion transport [UNKNOWN] behavior [IMP] regulation of long-term neuronal synaptic plasticity [UNKNOWN] long-term synaptic potentiation [IMP] long term synaptic depression [IMP] positive regulation of synaptic transmission, glutamatergic [IMP] calcium-mediated signaling [UNKNOWN] G-protein coupled receptor protein signaling pathway [IDA][IMP] response to cocaine [IMP] positive regulation of cAMP biosynthetic process [UNKNOWN] activation of phospholipase C activity by dopamine receptor signaling pathway [UNKNOWN][IDA][IGI] dentate gyrus development [IMP] mating behavior [IDA] protein import into nucleus [IMP] negative regulation of cell migration [UNKNOWN] positive regulation of cell migration [IMP] operant conditioning [UNKNOWN][IMP] activation of adenylate cyclase activity by dopamine receptor signaling pathway [IDA][IGI][IMP] astrocyte development [IMP] feeding behavior [IGI] cerebral cortex GABAergic interneuron migration [IMP] negative regulation of protein kinase activity [UNKNOWN] eating behavior [UNKNOWN] adult walking behavior [IGI][IMP] grooming behavior [IMP] locomotory behavior [UNKNOWN][IGI][IMP] synaptic transmission, dopaminergic [UNKNOWN][IMP] behavioral response to cocaine [UNKNOWN][IMP] [NOT]startle response [IMP] sensitization [IGI] muscle contraction [IMP] transmission of nerve impulse [IMP] activation of adenylate cyclase activity [IDA] regulation of action potential in neuron [IMP] [NOT]prepulse inhibition [IMP] signal transduction [IEA] negative regulation of circadian sleep/wake cycle, sleep [UNKNOWN] glucose import [IMP] hippocampus development [IMP] conditioned taste aversion [IMP] behavioral fear response [IMP] response to amphetamine [IGI][IMP] response to drug [IDA][IMP] regulation of dopamine metabolic process [IMP] temperature homeostasis [IMP] peristalsis [IGI]
Molecular Function:	G-protein coupled receptor activity [UNKNOWN][IDA] dopamine receptor activity [UNKNOWN][IDA] dopamine receptor activity, coupled via Gs [IMP] protein binding [IPI] drug binding [UNKNOWN] dopamine D1 receptor activity [UNKNOWN][IDA][IMP] receptor activity [IEA] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPNTSTMDE TGLPVERDFS FRILTACFLS LLILSTLLGN TLVCAAVIRF RHLRSKVTNF  60
   61 FVISLAVSDL LVAVLVMPWK AVAEIAGFWP FGSFCNIWVA FDIMCSTASI LNLCVISVDR 120
  121 YWAISSPFQY ERKMTPKAAF ILISVAWTLS VLISFIPVQL SWHKAKPTWP LDGNFTSLED 180
  181 AEDDNCDTRL SRTYAISSSL ISFYIPVAIM IVTYTSIYRI AQKQIRRISA LERAAVHAKN 240
  241 CQTTTGNGNP VECSQSESSF KMSFKRETKV LKTLSVIMGV FVCCWLPFFI SNCMVPFCGS 300
  301 EETQPFCIDS ITFDVFVWFG WANSSLNPII YAFNADFQKA FSTLLGCYRL CPTTNNAIET 360
  361 VSINNNGAVM FSSHHEPRGS ISKDCNLVYL IPHAVGSSED LKREEAGGIP KPLEKLSPAL 420
  421 SVILDYDTDV SLEKIQPVTH SGQHST

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: DRD1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: