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Protein Overview: NKX26_MOUSE

General Information:
Name(s) found: NKX26_MOUSE [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Homeobox protein Nkx-2.6 OS=Mus musculus GN=Nkx2-6 PE=2 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 289 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cellular_component [ND]
    Biological Process: multicellular organismal development [IEA]
    positive regulation of cell proliferation [IGI]
    regulation of transcription, DNA-dependent [IEA]
    hypothalamus development [IEPLink to PubMed article]
    embryonic heart tube development [IEPLink to PubMed article]
    tongue development [IEPLink to PubMed article]
    regulation of transcription [IEA]
    pharyngeal system development [IEPLink to PubMed articleLink to PubMed articleLink to PubMed article][IGI]
    pericardium development [IEPLink to PubMed article]
    heart development [IGI]
    gut development [IEPLink to PubMed article]
    negative regulation of apoptosis [IGI]
    cell differentiation [IGI]
    atrial cardiac muscle cell development [IEPLink to PubMed article]
    ventricular cardiac muscle cell development [IEPLink to PubMed article]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IEA]
    transcription regulator activity [IEA]
    sequence-specific DNA binding [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSSPVASTP FSVADILRLE CQQKDSKTLS QWELHRNPVK PRYLRMNQES GWFESSDRAQ  60
   61 AVPFRCTWET VLEMGSNPVG EPQTPPGTIS RLGARNPMTD RGVGNLSGDM RRGGPVSTRT 120
  121 RPQRKSRVLF SQAQVLALER RFKQQRYLTA PEREHLASAL QLTSTQVKIW FQNRRYKSKS 180
  181 QRQDQTLELA GHPLAPRRVA VPVLVLDGKP CLDPDVAAFL GPYKATSPYS CFGGYAGTPY 240
  241 DASYASRCTS ASAGPGPLTP LASSGFSPGG QSAAPQGHLP ATPQGVTAW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle