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Protein Overview: CD3D_MOUSE

General Information:
Name(s) found: CD3D_MOUSE [Swiss-Prot]
Description(s) found:
Found 32 descriptions.
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  • T-cell surface glycoprotein CD3 delta chain OS=Mus musculus GN=Cd3d PE=3 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 173 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    T cell receptor complex [UNKNOWN][NAS]
    alpha-beta T cell receptor complex [IDA]
    Biological Process: protein complex assembly [NAS]
    T cell activation [NAS]
    cell surface receptor linked signaling pathway [IEA]
    positive thymic T cell selection [IMP]
    Molecular Function: transmembrane receptor activity [IEA]
    protein binding [IPI]
    receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHSGILASL ILIAVLPQGS PFKIQVTEYE DKVFVTCNTS VMHLDGTVEG WFAKNKTLNL  60
   61 GKGVLDPRGI YLCNGTEQLA KVVSSVQVHY RMCQNCVELD SGTMAGVIFI DLIATLLLAL 120
  121 GVYCFAGHET GRPSGAAEVQ ALLKNEQLYQ PLRDREDTQY SRLGGNWPRN KKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] PSI-BLAST 6.045757 Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment
    2 View Details [99..173] PSI-BLAST 4.69897 No description for 2dm3A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  4.00123250685257 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.81769911097805 bayes_pls_golite062009
  • antigen binding
    		•  3.16266926144655 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • signal transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • binding
    		•  2.53652619212064 bayes_pls_golite062009
  • T cell receptor binding
    		•  2.12089279430732 bayes_pls_golite062009
  • peptide antigen binding
    		•  1.66960790017756 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.02428106476324 bayes_pls_golite062009
  • receptor binding
    		•  0.909733688848793 bayes_pls_golite062009
  • immunoglobulin binding
    		•  0.84834833214265 bayes_pls_golite062009
  • protein complex binding
    		•  0.83543827718565 bayes_pls_golite062009
  • peptide binding
    		•  0.729048089532569 bayes_pls_golite062009
  • coreceptor activity
    		•  0.661209696849389 bayes_pls_golite062009
  • growth factor binding
    		•  0.53454839799174 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.447829399094714 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.28309679787333 bayes_pls_golite062009
  • olfactory receptor activity
    		•  0.20101044847022 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle