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Protein Overview: HMGB3_MOUSE

General Information:
Name(s) found: HMGB3_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74194280|dbj|BAE24671.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74192972|dbj|BAE34988.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74186760|dbj|BAE34835.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74146994|dbj|BAE27437.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6680231|ref|NP_032279.1| high mobility group box 3 [Mus musculus] [NCBI NR]
  • gi|54035419|gb|AAH83352.1| High mobility group box 3 [Mus musculus] [NCBI NR]
  • gi|2738989|gb|AAC16925.1| high mobility group protein homolog HMG4 [Mus musculus] [NCBI NR]
  • gi|26327985|dbj|BAC27733.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|20138160|sp|O54879.3|HMGB3_MOUSE RecName: Full=High mobility group protein B3; AltName: Full=High mobility group protein 4; Short=HMG-4; AltName: Full=High mobility group protein 2a; Short=HMG-2a [NCBI NR]
  • gi|187957408|gb|AAI58038.1| High mobility group box 3 [Mus musculus] [NCBI NR]
  • gi|15030059|gb|AAH11276.1| Hmgb3 protein [Mus musculus] [NCBI NR]
  • gi|148694628|gb|EDL26575.1| mCG10155, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|148694626|gb|EDL26573.1| mCG10155, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|123230264|emb|CAM25454.1| high mobility group box 3 [Mus musculus] [NCBI NR]
  • High mobility group protein B3 OS=Mus musculus GN=Hmgb3 PE=1 SV=3 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):X-55763135;1-4887712 high mobility group box 3 [hmr_yeast5_DM3-1_pombe.fasta]
  • high mobility group box 3; high mobilty group protein 2A; high-mobility group protein 4 [HMR_022704-rand.fasta]
  • Hmgb3 protein [Mus musculus]gi|6680231|ref|NP_032279.1| high mobility group box 3 [Mus musculus]gi|54035419|gb|AAH83352.1| High mobility group box 3 [Mus musculus]gi|20138160|sp|O54879|HMG4_MOUSE High mobility group protein 4 (HMG-4) (High mobility gro [nrdb_11152004_Chlamydomonas]
  • (NM_008253) high mobility group box 3; high mobilty group protein 2A; high-mobility group protein 4 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • high mobility group box 3 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • High mobility group box 3 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG10155, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Hmgb3 protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • high mobility group protein homolog HMG4 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 HIGH MOBILITY GROUP BOX 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Hmgb3 High mobility group protein B3 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Hmgb3 High mobility group protein B3 ENSMUSG00000015217 IPI00669631 IPI00228879 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • high mobility group protein B3 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00228879.7|SWISS-PROT:O54879|TREMBL:Q544R9|ENSEMBL:ENSMUSP00000015361;ENSMUSP00000086260;ENSMUSP00000110229;ENSMUSP00000110232|REFSEQ:NP_032279|VEGA:OTTMUSP00000019352;OTTMUSP00000019353;OTTMUSP00000019354;OTTMUSP00000019355 Tax_Id=10090 Gene_Symbol=Hmgb3 High mobility group protein B3 [ipi.MOUSE.fasta.20090209]
  • High mobility group protein B3 OS=Mus musculus GN=Hmgb3 [011711_HMR.fasta]
  • High mobility group protein B3 OS=Mus musculus GN=Hmgb3 PE=2 SV=3 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • sp|O54879|HMGB3_MOUSE High mobility group protein B3 OS=Mus musculus GN=Hmgb3 PE=2 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|Q544R9|Q544R9_MOUSE High mobility group box 3 OS=Mus musculus GN=Hmgb3 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • High mobility group box 3 OS=Mus musculus GN=Hmgb3 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of O54879, High mobility group box 3 OS=Mus musculus GN=Hmgb3 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 200 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKGDPKKPK GKMSAYAFFV QTCREEHKKK NPEVPVNFAE FSKKCSERWK TMSSKEKSKF  60
   61 DEMAKADKVR YDREMKDYGP AKGGKKKKDP NAPKRPPSGF FLFCSEFRPK IKSTNPGISI 120
  121 GDVAKKLGEM WNNLSDNEKQ PYVTKAAKLK EKYEKDVADY KSKGKFDGAK GPAKVARKKV 180
  181 EEEEEEEEEE EEEEEEEEDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..200] PSI-BLAST 26.69897 No description for 2gzkA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • open form four-way junction DNA binding
    		•  5.94145823677022 bayes_pls_golite062009
  • crossed form four-way junction DNA binding
    		•  5.94145823677022 bayes_pls_golite062009
  • bent DNA binding
    		•  5.94145823677022 bayes_pls_golite062009
  • DNA binding
    		•  5.15324651287773 bayes_pls_golite062009
  • calcium-dependent protein kinase regulator activity
    		•  5.14145584261223 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.01228762819617 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.9607192917135 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82658263870186 bayes_pls_golite062009
  • binding
    		•  3.6211482127468 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.96229555092695 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.75319687398598 bayes_pls_golite062009
  • chromatin binding
    		•  1.64428658020027 bayes_pls_golite062009
  • transcription activator activity
    		•  1.62744929149746 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.53825678633232 bayes_pls_golite062009
  • protein binding
    		•  1.131658134984 bayes_pls_golite062009
  • transcription factor binding
    		•  1.10315330167937 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.97864089342287 bayes_pls_golite062009
  • DNA bending activity
    		•  0.87985209274756 bayes_pls_golite062009
  • four-way junction DNA binding
    		•  0.322458571311759 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.261169200304829 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle