General Information: |
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Name(s) found: |
TLR1_MOUSE
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Mus musculus |
Length: | 795 amino acids |
Gene Ontology: |
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Cellular Component: |
Toll-like receptor 1-Toll-like receptor 2 protein complex
[UNKNOWN]
membrane [NAS] integral to membrane [IEA] phagocytic vesicle [NAS] cytoplasmic vesicle [IEA] intrinsic to membrane [IEA] plasma membrane [IEA] |
Biological Process: |
cellular response to triacylated bacterial lipopeptide
[UNKNOWN]
inflammatory response [IEA] immune response [IEA] signal transduction [IEA] innate immune response [IEA] activation of NF-kappaB-inducing kinase activity [NAS] detection of triacylated bacterial lipopeptide [UNKNOWN][NAS] positive regulation of interleukin-6 biosynthetic process [IMP] defense response [IMP] macrophage activation [NAS] positive regulation of tumor necrosis factor biosynthetic process [IMP] |
Molecular Function: |
transmembrane receptor activity
[NAS]
protein binding [IEA] protein heterodimerization activity [UNKNOWN] triacylated lipopeptide binding [NAS] receptor activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MTKPNSLIFY CIIVLGLTLM KIQLSEECEL IIKRPNANLT RVPKDLPLQT TTLDLSQNNI 60 61 SELQTSDILS LSKLRVLIMS YNRLQYLNIS VFKFNTELEY LDLSHNELKV ILCHPTVSLK 120 121 HLDLSFNAFD ALPICKEFGN MSQLQFLGLS GSRVQSSSVQ LIAHLNISKV LLVLGDAYGE 180 181 KEDPESLRHV STETLHIVFP SKREFRFLLD VSVSTTIGLE LSNIKCVLED QGCSYFLRAL 240 241 SKLGKNLKLS NLTLNNVETT WNSFINILQI VWHTPVKYFS ISNVKLQGQL AFRMFNYSDT 300 301 SLKALSIHQV VTDVFSFPQS YIYSIFANMN IQNFTMSGTH MVHMLCPSQV SPFLHVDFTD 360 361 NLLTDMVFKD CRNLVRLKTL SLQKNQLKNL ENIILTSAKM TSLQKLDISQ NSLRYSDGGI 420 421 PCAWTQSLLV LNLSSNMLTG SVFRCLPPKV KVLDLHNNRI MSIPKDVTHL QALQELNVAS 480 481 NSLTDLPGCG AFSSLSVLVI DHNSVSHPSE DFFQSCQNIR SLTAGNNPFQ CTCELRDFVK 540 541 NIGWVAREVV EGWPDSYRCD YPESSRGTAL RDFHMSPLSC DTVLLTVTIG ATMLVLAVTG 600 601 AFLCLYFDLP WYVRMLCQWT QTRHRARHIP LEELQRNLQF HAFVSYSGHD SAWVKNELLP 660 661 NLEKDDIQIC LHERNFVPGK SIVENIINFI EKSYKSIFVL SPHFIQSEWC HYELYFAHHN 720 721 LFHEGSDNLI LILLAPIPQY SIPTNYHKLK TLMSRRTYLE WPTEKNKHGL FWANLRASIN 780 781 VKLVNQAEGT CYTQQ |
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