Protein Overview: TLR1_MOUSE

General Information:
Name(s) found:	TLR1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|223462782\|gb\|AAI41322.1\| Toll-like receptor 1 [Mus musculus] [NCBI NR] gi\|223461575\|gb\|AAI41320.1\| Toll-like receptor 1 [Mus musculus] [NCBI NR] gi\|20140791\|sp\|Q9EPQ1.1\|TLR1_MOUSE RecName: Full=Toll-like receptor 1; AltName: Full=Toll/interleukin-1 receptor-like protein; Short=TIL; AltName: CD_antigen=CD281; Flags: Precursor [NCBI NR] gi\|148705776\|gb\|EDL37723.1\| toll-like receptor 1, isoform CRA_a [Mus musculus] [NCBI NR] gi\|148705775\|gb\|EDL37722.1\| toll-like receptor 1, isoform CRA_a [Mus musculus] [NCBI NR] gi\|13507603\|ref\|NP_109607.1\| toll-like receptor 1 [Mus musculus] [NCBI NR] gi\|11528627\|gb\|AAG37302.1\| toll-like receptor 1 [Mus musculus] [NCBI NR] Toll-like receptor 1 OS=Mus musculus GN=Tlr1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):5-63949537 Toll-like receptor 1 precursor [hmr_yeast5_DM3-1_pombe.fasta] toll-like receptor 1 [HMR_022704-rand.fasta] toll-like receptor 1 [Mus musculus]gi\|20140791\|sp\|Q9EPQ1\|TLR1_MOUSE Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like) (TIL)gi\|11528627\|gb\|AAG37302.1\| toll-like receptor 1 [Mus musculus] [nrdb_11152004_Chlamydomonas] Toll-like receptor 1 precursor [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Toll-like receptor 1 precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_030682) toll-like receptor 1 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] toll-like receptor 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] toll-like receptor 1, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 TOLL-LIKE RECEPTOR 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Tlr1 Toll-like receptor 1 [mouse-ipi-250309-contam.fasta] toll-like receptor 1 precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Tlr1 Toll-like receptor 1 precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Tlr1 Toll-like receptor 1 precursor ENSMUSG00000044827 IPI00110218 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00110218.1\|SWISS-PROT:Q9EPQ1\|TREMBL:Q6A0E8\|ENSEMBL:ENSMUSP00000060793\|REFSEQ:NP_109607 Tax_Id=10090 Gene_Symbol=Tlr1 Toll-like receptor 1 [ipi.MOUSE.fasta.20090209] Toll-like receptor 1 OS=Mus musculus GN=Tlr1 [011711_HMR.fasta] sp\|Q9EPQ1\|TLR1_MOUSE Toll-like receptor 1 OS=Mus musculus GN=Tlr1 PE=1 SV=1 [uniprot.sptr.mouse.20130102] tr\|B9EJ46\|B9EJ46_MOUSE Toll-like receptor OS=Mus musculus GN=Tlr1 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Toll-like receptor OS=Mus musculus GN=Tlr1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Toll-like receptor 1 OS=Mus musculus GN=Tlr1 PE=2 SV=1 [UniProt_mouse_01-27-2011_reversed.fasta] Isoform of Q9EPQ1, Toll-like receptor OS=Mus musculus GN=Tlr1 PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	795 amino acids
Gene Ontology:
Cellular Component:	Toll-like receptor 1-Toll-like receptor 2 protein complex [UNKNOWN] membrane [NAS] integral to membrane [IEA] phagocytic vesicle [NAS] cytoplasmic vesicle [IEA] intrinsic to membrane [IEA] plasma membrane [IEA]
Biological Process:	cellular response to triacylated bacterial lipopeptide [UNKNOWN] inflammatory response [IEA] immune response [IEA] signal transduction [IEA] innate immune response [IEA] activation of NF-kappaB-inducing kinase activity [NAS] detection of triacylated bacterial lipopeptide [UNKNOWN][NAS] positive regulation of interleukin-6 biosynthetic process [IMP] defense response [IMP] macrophage activation [NAS] positive regulation of tumor necrosis factor biosynthetic process [IMP]
Molecular Function:	transmembrane receptor activity [NAS] protein binding [IEA] protein heterodimerization activity [UNKNOWN] triacylated lipopeptide binding [NAS] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKPNSLIFY CIIVLGLTLM KIQLSEECEL IIKRPNANLT RVPKDLPLQT TTLDLSQNNI  60
   61 SELQTSDILS LSKLRVLIMS YNRLQYLNIS VFKFNTELEY LDLSHNELKV ILCHPTVSLK 120
  121 HLDLSFNAFD ALPICKEFGN MSQLQFLGLS GSRVQSSSVQ LIAHLNISKV LLVLGDAYGE 180
  181 KEDPESLRHV STETLHIVFP SKREFRFLLD VSVSTTIGLE LSNIKCVLED QGCSYFLRAL 240
  241 SKLGKNLKLS NLTLNNVETT WNSFINILQI VWHTPVKYFS ISNVKLQGQL AFRMFNYSDT 300
  301 SLKALSIHQV VTDVFSFPQS YIYSIFANMN IQNFTMSGTH MVHMLCPSQV SPFLHVDFTD 360
  361 NLLTDMVFKD CRNLVRLKTL SLQKNQLKNL ENIILTSAKM TSLQKLDISQ NSLRYSDGGI 420
  421 PCAWTQSLLV LNLSSNMLTG SVFRCLPPKV KVLDLHNNRI MSIPKDVTHL QALQELNVAS 480
  481 NSLTDLPGCG AFSSLSVLVI DHNSVSHPSE DFFQSCQNIR SLTAGNNPFQ CTCELRDFVK 540
  541 NIGWVAREVV EGWPDSYRCD YPESSRGTAL RDFHMSPLSC DTVLLTVTIG ATMLVLAVTG 600
  601 AFLCLYFDLP WYVRMLCQWT QTRHRARHIP LEELQRNLQF HAFVSYSGHD SAWVKNELLP 660
  661 NLEKDDIQIC LHERNFVPGK SIVENIINFI EKSYKSIFVL SPHFIQSEWC HYELYFAHHN 720
  721 LFHEGSDNLI LILLAPIPQY SIPTNYHKLK TLMSRRTYLE WPTEKNKHGL FWANLRASIN 780
  781 VKLVNQAEGT CYTQQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TLR1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: