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Protein Overview: SENP8_MOUSE

General Information:
Name(s) found: SENP8_MOUSE [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • Sentrin-specific protease 8 OS=Mus musculus GN=Senp8 PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 221 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    proteolysis [IEA]
    Molecular Function: NEDD8-specific protease activity [UNKNOWN]
    cysteine-type peptidase activity [UNKNOWN]
    peptidase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPVVLSYMD SLLRQSDVSL LDPPSWLNDH IIGFAFEYFA NSQFHDCSDH VCFISPEVTQ  60
   61 FIKCTSSPAE IAMFLEPLDL PHKRVVFLAI NDNSNQAAGG THWSLLVYLQ DKNSFFHYDS 120
  121 HSRSNSIHAK QVAEKLKAFL GSKGDKLVFV EEKAPAQENS YDCGMYVICN TEALCQSLFR 180
  181 RQPESPLQLL TPTYITKKRG EWKDLIARLA KKNEVATEEC S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..221] PSI-BLAST 41.0 NEDD8 protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  5.93560668185539 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  5.48721952122524 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  4.73623517114533 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  3.38737606974088 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.90178501880966 bayes_pls_golite062009
  • SUMO-specific protease activity
    		•  1.6602460763044 bayes_pls_golite062009
  • peptidase activity
    		•  1.39702589518384 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.28597643058503 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • protein binding
    		•  0.755467947031123 bayes_pls_golite062009
  • hydrolase activity
    		•  0.612664640888088 bayes_pls_golite062009
  • binding
    		•  0.426262567794169 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.366512660710683 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  0.125393771316362 bayes_pls_golite062009
  • NEDD8-specific protease activity
    		•  0.09564496961635 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle